PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy

by Iris C. Salaroglio, Elisa Panada, Enrico Moiso, Ilaria Buondonno, Paolo Provero, Menachem Rubinstein, Joanna Kopecka, Chiara Riganti
Published 2017-05-01

New Tetrahydroisoquinoline Derivatives Overcome Pgp Activity in Brain-Blood Barrier and Glioblastoma Multiforme in Vitro

by Iris Chiara Salaroglio, Elena Gazzano, Joanna Kopecka, Konstantin Chegaev, Costanzo Costamagna, Roberta Fruttero, Stefano Guglielmo, Chiara Riganti
Published 2018-06-01

Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells.

by Chiara Riganti, Barbara Castella, Joanna Kopecka, Ivana Campia, Marta Coscia, Gianpiero Pescarmona, Amalia Bosia, Dario Ghigo, Massimo Massaia
Published 2013-01-01

Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death

by Joanna Kopecka, Martina Godel, Silvia Dei, Roberta Giampietro, Dimas Carolina Belisario, Muhlis Akman, Marialessandra Contino, Elisabetta Teodori, Chiara Riganti
Published 2020-04-01

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

by Elisabetta Muntoni, Katia Martina, Elisabetta Marini, Marta Giorgis, Loretta Lazzarato, Iris Chiara Salaroglio, Chiara Riganti, Michele Lanotte, Luigi Battaglia
Published 2019-02-01

The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells

by Barbara Castella, Joanna Kopecka, Patrizia Sciancalepore, Giorgia Mandili, Myriam Foglietta, Nico Mitro, Donatella Caruso, Francesco Novelli, Chiara Riganti, Massimo Massaia
Published 2017-06-01

From single gene analysis to single cell profiling: a new era for precision medicine

by Maria Teresa Di Martino, Stefania Meschini, Katia Scotlandi, Chiara Riganti, Enrico De Smaele, Francesca Zazzeroni, Massimo Donadelli, Carlo Leonetti, Michele Caraglia
Published 2020-03-01

Combination of PDT and NOPDT with a Tailored BODIPY Derivative

by Loretta Lazzarato, Elena Gazzano, Marco Blangetti, Aurore Fraix, Federica Sodano, Giulia Maria Picone, Roberta Fruttero, Alberto Gasco, Chiara Riganti, Salvatore Sortino
Published 2019-11-01

Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting

by Elisabeth Wyart, Simone Reano, Myriam Y. Hsu, Dario Livio Longo, Mingchuan Li, Emilio Hirsch, Nicoletta Filigheddu, Alessandra Ghigo, Chiara Riganti, Paolo Ettore Porporato
Published 2018-01-01

A regulatory microRNA network controls endothelial cell phenotypic switch during sprouting angiogenesis

by Stefania Rosano, Davide Corà, Sushant Parab, Serena Zaffuto, Claudio Isella, Roberta Porporato, Roxana Maria Hoza, Raffaele A Calogero, Chiara Riganti, Federico Bussolino, Alessio Noghero
Published 2020-01-01

Calcitriol Inhibits Viability and Proliferation in Human Malignant Pleural Mesothelioma Cells

by Iacopo Gesmundo, Francesca Silvagno, Dana Banfi, Valentina Monica, Valentina Monica, Alessandro Fanciulli, Giacomo Gamba, Noemi Congiusta, Roberta Libener, Chiara Riganti, Ezio Ghigo, Riccarda Granata
Published 2020-10-01

NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

by Valentina Audrito, Vincenzo Gianluca Messana, Enrico Moiso, Nicoletta Vitale, Francesca Arruga, Lorenzo Brandimarte, Federica Gaudino, Elisa Pellegrino, Tiziana Vaisitti, Chiara Riganti, Roberto Piva, Silvia Deaglio
Published 2020-12-01

Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma

by Martina Godel, Deborah Morena, Preeta Ananthanarayanan, Ilaria Buondonno, Giulio Ferrero, Claudia M. Hattinger, Federica Di Nicolantonio, Massimo Serra, Riccardo Taulli, Francesca Cordero, Chiara Riganti, Joanna Kopecka
Published 2020-06-01

Targeting HIF-1α Regulatory Pathways as a Strategy to Hamper Tumor-Microenvironment Interactions in CLL

by Candida Vitale, Valentina Griggio, Chiara Riganti, Maria Todaro, Joanna Kopecka, Rebecca Jones, Chiara Salvetti, Elia Boccellato, Francesca Perutelli, Claudia Voena, Laura Godio, Mario Boccadoro, Marta Coscia
Published 2021-06-01

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers

by Laura Braconi, Gianluca Bartolucci, Marialessandra Contino, Niccolò Chiaramonte, Roberta Giampietro, Dina Manetti, Maria Grazia Perrone, Maria Novella Romanelli, Nicola Antonio Colabufo, Chiara Riganti, Silvia Dei, Elisabetta Teodori
Published 2020-01-01

Sphingolipid Synthesis Inhibition by Myriocin Administration Enhances Lipid Consumption and Ameliorates Lipid Response to Myocardial Ischemia Reperfusion Injury

by Fabiola Bonezzi, Marco Piccoli, Michele Dei Cas, Rita Paroni, Alessandra Mingione, Michelle M. Monasky, Anna Caretti, Chiara Riganti, Riccardo Ghidoni, Carlo Pappone, Luigi Anastasia, Luigi Anastasia, Paola Signorelli
Published 2019-08-01

Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer

by Iris C. Salaroglio, Elena Gazzano, Ahmad Abdullrahman, Eleonora Mungo, Barbara Castella, Gamal Eldein Fathy Abd-ellatef Abd-elrahman, Massimo Massaia, Massimo Donadelli, Menachem Rubinstein, Chiara Riganti, Joanna Kopecka
Published 2018-11-01

ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma

by Dimas Carolina Belisario, Muhlis Akman, Martina Godel, Virginia Campani, Maria Pia Patrizio, Lorena Scotti, Claudia Maria Hattinger, Giuseppe De De Rosa, Massimo Donadelli, Massimo Serra, Joanna Kopecka, Chiara Riganti
Published 2020-03-01

Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

by Moitza Principe, Simone Borgoni, Mariafrancesca Cascione, Michelle Samuel Chattaragada, Sammy Ferri-Borgogno, Michela Capello, Sara Bulfamante, Jennifer Chapelle, Francesca Di Modugno, Paola Defilippi, Paola Nisticò, Paola Cappello, Chiara Riganti, Stefano Leporatti, Francesco Novelli
Published 2017-01-01

Predialysis and Dialysis Therapies Differently Affect Nitric Oxide Synthetic Pathway in Red Blood Cells from Uremic Patients: Focus on Peritoneal Dialysis

by Carola Palmerini, Luca Piscitani, Giuseppina Bologna, Chiara Riganti, Paola Lanuti, Domitilla Mandatori, Lorenzo Di Liberato, Giorgia Di Fulvio, Vittorio Sirolli, Giulia Renda, Caterina Pipino, Marco Marchisio, Mario Bonomini, Assunta Pandolfi, Natalia Di Pietro
Published 2021-03-01