Coronary Artery Disease is More Severe in Patients with Non-Alcoholic Steatohepatitis than Fatty Liver

by Toshihiro Niikura, Kento Imajo, Anna Ozaki, Takashi Kobayashi, Michihiro Iwaki, Yasushi Honda, Takaomi Kessoku, Yuji Ogawa, Masato Yoneda, Hiroyuki Kirikoshi, Satoru Saito, Atsushi Nakajima
Published 2020-02-01

The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice.

by Yasushi Honda, Kento Imajo, Takayuki Kato, Takaomi Kessoku, Yuji Ogawa, Wataru Tomeno, Shingo Kato, Hironori Mawatari, Koji Fujita, Masato Yoneda, Satoru Saito, Atsushi Nakajima
Published 2016-01-01

Air quality co-benefits from climate mitigation for human health in South Korea

by Satbyul Estella Kim, Yang Xie, Hancheng Dai, Shinichiro Fujimori, Yasuaki Hijioka, Yasushi Honda, Masahiro Hashizume, Toshihiko Masui, Tomoko Hasegawa, Xinghan Xu, Kan Yi, Ho Kim
Published 2020-03-01

Protective effect of SGL5213, a potent intestinal sodium–glucose cotransporter 1 inhibitor, in nonalcoholic fatty liver disease in mice

by Yasushi Honda, Anna Ozaki, Michihiro Iwaki, Takashi Kobayashi, Asako Nogami, Takaomi Kessoku, Yuji Ogawa, Wataru Tomeno, Kento Imajo, Masato Yoneda, Satoru Saito, Yoji Nagashima, Atsushi Nakajima
Published 2021-10-01

Rationale and design of a randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated phase 2a study to investigate the efficacy and safety of elobixibat i...

by Takeharu Yamanaka, Koji Yamamoto, Yasushi Honda, Kento Imajo, Yuji Ogawa, Takaomi Kessoku, Takashi Kobayashi, Anna Ozaki, Satoru Saito, Michihiro Iwaki, Yusuke Saigusa, Haruki Usuda, Koichiro Wada
Published 2020-09-01

Characterizing the relationship between temperature and mortality in tropical and subtropical cities: a distributed lag non-linear model analysis in Hue, Viet Nam, 2009–2013

by Tran Ngoc Dang, Xerxes T. Seposo, Nguyen Huu Chau Duc, Tran Binh Thang, Do Dang An, Lai Thi Minh Hang, Tran Thanh Long, Bui Thi Hong Loan, Yasushi Honda
Published 2016-01-01

Lubiprostone improves intestinal permeability in humans, a novel therapy for the leaky gut: A prospective randomized pilot study in healthy volunteers.

by Takayuki Kato, Yasushi Honda, Yusuke Kurita, Akito Iwasaki, Takamitsu Sato, Takaomi Kessoku, Shiori Uchiyama, Yuji Ogawa, Hidenori Ohkubo, Takuma Higurashi, Takeharu Yamanaka, Haruki Usuda, Koichiro Wada, Atsushi Nakajima
Published 2017-01-01

Effect of tofogliflozin and pioglitazone on hepatic steatosis in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus: A randomized, open-label pilot study (ToP...

by Anna Ozaki, Masato Yoneda, Takaomi Kessoku, Michihiro Iwaki, Takashi Kobayashi, Yasushi Honda, Yuji Ogawa, Kento Imajo, Eiji Sakai, Masataka Taguri, Takeharu Yamanaka, Tomoyuki Iwasaki, Takeo Kurihashi, Satoru Saito, Atsushi Nakajima
Published 2020-03-01

Complications of Non-Alcoholic Fatty Liver Disease in Extrahepatic Organs

by Wataru Tomeno, Kento Imajo, Takuya Takayanagi, Yu Ebisawa, Kosuke Seita, Tsuneyuki Takimoto, Kanami Honda, Takashi Kobayashi, Asako Nogami, Takayuki Kato, Yasushi Honda, Takaomi Kessoku, Yuji Ogawa, Hiroyuki Kirikoshi, Yasunari Sakamoto, Masato Yoneda, Satoru Saito, Atsushi Nakajima
Published 2020-11-01

Comparing the effectiveness of magnesium oxide and naldemedine in preventing opioid-induced constipation: a proof of concept, single institutional, two arm, open-label, phase II, r...

by Anna Ozaki, Takaomi Kessoku, Michihiro Iwaki, Takashi Kobayashi, Tsutomu Yoshihara, Takayuki Kato, Yasushi Honda, Yuji Ogawa, Kento Imajo, Takuma Higurashi, Masato Yoneda, Masataka Taguri, Takeharu Yamanaka, Hiroto Ishiki, Noritoshi Kobayashi, Satoru Saito, Yasushi Ichikawa, Atsushi Nakajima
Published 2020-06-01

LDL-migration index (LDL-MI), an indicator of small dense low-density lipoprotein (sdLDL), is higher in non-alcoholic steatohepatitis than in non-alcoholic fatty liver: a multicent...

by Kento Imajo, Hideyuki Hyogo, Masato Yoneda, Yasushi Honda, Takaomi Kessoku, Wataru Tomeno, Yuji Ogawa, Masataka Taguri, Hironori Mawatari, Yuichi Nozaki, Koji Fujita, Hiroyuki Kirikoshi, Satoru Saito, Yoshio Sumida, Masafumi Ono, Koichiro Wada, Atsushi Nakajima, Yuichiro Eguchi
Published 2014-01-01

The Role of Leaky Gut in Nonalcoholic Fatty Liver Disease: A Novel Therapeutic Target

by Takaomi Kessoku, Takashi Kobayashi, Kosuke Tanaka, Atsushi Yamamoto, Kota Takahashi, Michihiro Iwaki, Anna Ozaki, Yuki Kasai, Asako Nogami, Yasushi Honda, Yuji Ogawa, Shingo Kato, Kento Imajo, Takuma Higurashi, Kunihiro Hosono, Masato Yoneda, Haruki Usuda, Koichiro Wada, Satoru Saito, Atsushi Nakajima
Published 2021-07-01

Can magnifying endoscopy with narrow-band imaging discriminate between carcinomas and low grade adenomas in gastric superficial elevated lesions?

by Takashi Nonaka, Masahiko Inamori, Yasushi Honda, Kenji Kanoshima, Yumi Inoh, Mizue Matsuura, Shiori Uchiyama, Eiji Sakai, Takuma Higurashi, Hidenori Ohkubo, Hiroshi Iida, Hiroki Endo, Koji Fujita, Akihiko Kusakabe, Kazuhiro Atsukawa, Hisao Takahashi, Yoko Tateishi, Shin Maeda, Kenichi Ohashi, Atsushi Nakajima
Published 2016-10-01

Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study

by Yasushi Honda, Takaomi Kessoku, Yoshio Sumida, Takashi Kobayashi, Takayuki Kato, Yuji Ogawa, Wataru Tomeno, Kento Imajo, Koji Fujita, Masato Yoneda, Koshi Kataoka, Masataka Taguri, Takeharu Yamanaka, Yuya Seko, Saiyu Tanaka, Satoru Saito, Masafumi Ono, Satoshi Oeda, Yuichiro Eguchi, Wataru Aoi, Kenji Sato, Yoshito Itoh, Atsushi Nakajima
Published 2017-08-01

A multi-country analysis on potential adaptive mechanisms to cold and heat in a changing climate

by Ana M. Vicedo-Cabrera, Francesco Sera, Yuming Guo, Yeonseung Chung, Katherine Arbuthnott, Shilu Tong, Aurelio Tobias, Eric Lavigne, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Patrick G. Goodman, Ariana Zeka, Masahiro Hashizume, Yasushi Honda, Ho Kim, Martina S. Ragettli, Martin Röösli, Antonella Zanobetti, Joel Schwartz, Ben Armstrong, Antonio Gasparrini
Published 2018-02-01

Common Drug Pipelines for the Treatment of Diabetic Nephropathy and Hepatopathy: Can We Kill Two Birds with One Stone?

by Yoshio Sumida, Masashi Yoneda, Hidenori Toyoda, Satoshi Yasuda, Toshifumi Tada, Hideki Hayashi, Yoichi Nishigaki, Yusuke Suzuki, Takafumi Naiki, Asahiro Morishita, Hiroshi Tobita, Shuichi Sato, Naoto Kawabe, Shinya Fukunishi, Tadashi Ikegami, Takaomi Kessoku, Yuji Ogawa, Yasushi Honda, Takashi Nakahara, Kensuke Munekage, Tsunehiro Ochi, Koji Sawada, Atsushi Takahashi, Taeang Arai, Tomomi Kogiso, Satoshi Kimoto, Kengo Tomita, Kazuo Notsumata, Michihiro Nonaka, Kazuhito Kawata, Taro Takami, Takashi Kumada, Eiichi Tomita, Takeshi Okanoue, Atsushi Nakajima, Japan Study Group of NAFLD (JSG-NAFLD)
Published 2020-07-01

Quantifying excess deaths related to heatwaves under climate change scenarios: A multicountry time series modelling study.

by Yuming Guo, Antonio Gasparrini, Shanshan Li, Francesco Sera, Ana Maria Vicedo-Cabrera, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Eric Lavigne, Benjawan Tawatsupa, Kornwipa Punnasiri, Ala Overcenco, Patricia Matus Correa, Nicolas Valdes Ortega, Haidong Kan, Samuel Osorio, Jouni J K Jaakkola, Niilo R I Ryti, Patrick G Goodman, Ariana Zeka, Paola Michelozzi, Matteo Scortichini, Masahiro Hashizume, Yasushi Honda, Xerxes Seposo, Ho Kim, Aurelio Tobias, Carmen Íñiguez, Bertil Forsberg, Daniel Oudin Åström, Yue Leon Guo, Bing-Yu Chen, Antonella Zanobetti, Joel Schwartz, Tran Ngoc Dang, Dung Do Van, Michelle L Bell, Ben Armstrong, Kristie L Ebi, Shilu Tong
Published 2018-07-01

Predicted temperature-increase-induced global health burden and its regional variability

by Jae Young Lee, Ho Kim, Antonio Gasparrini, Ben Armstrong, Michelle L. Bell, Francesco Sera, Eric Lavigne, Rosana Abrutzky, Shilu Tong, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Patricia Matus Correa, Nicolas Valdes Ortega, Haidong Kan, Samuel Osorio Garcia, Jan Kyselý, Aleš Urban, Hans Orru, Ene Indermitte, Jouni J.K. Jaakkola, Niilo R.I. Ryti, Mathilde Pascal, Patrick G. Goodman, Ariana Zeka, Paola Michelozzi, Matteo Scortichini, Masahiro Hashizume, Yasushi Honda, Magali Hurtado, Julio Cruz, Xerxes Seposo, Baltazar Nunes, João Paulo Teixeira, Aurelio Tobias, Carmen Íñiguez, Bertil Forsberg, Christofer Åström, Ana Maria Vicedo-Cabrera, Martina S. Ragettli, Yue-Liang Leon Guo, Bing-Yu Chen, Antonella Zanobetti, Joel Schwartz, Tran Ngoc Dang, Dung Do Van, Fetemeh Mayvaneh, Ala Overcenco, Shanshan Li, Yuming Guo
Published 2019-10-01

Ambient carbon monoxide and daily mortality: a global time-series study in 337 cities

by Kai Chen, PhD, Susanne Breitner, PhD, Kathrin Wolf, PhD, Massimo Stafoggia, PhD, Francesco Sera, MSc, Ana M Vicedo-Cabrera, PhD, Yuming Guo, ProfPhD, Shilu Tong, ProfPhD, Eric Lavigne, ProfPhD, Patricia Matus, PhD, Nicolás Valdés, MSc, Haidong Kan, ProfPhD, Jouni J K Jaakkola, ProfPhD, Niilo R I Ryti, PhD, Veronika Huber, PhD, Matteo Scortichini, MSc, Masahiro Hashizume, ProfPhD, Yasushi Honda, ProfPhD, Baltazar Nunes, PhD, Joana Madureira, PhD, Iulian Horia Holobâcă, PhD, Simona Fratianni, PhD, Ho Kim, ProfPhD, Whanhee Lee, PhD, Aurelio Tobias, PhD, Carmen Íñiguez, PhD, Bertil Forsberg, ProfPhD, Christofer Åström, PhD, Martina S Ragettli, PhD, Yue-Liang Leon Guo, ProfPhD, Bing-Yu Chen, PhD, Shanshan Li, PhD, Ai Milojevic, PhD, Antonella Zanobetti, PhD, Joel Schwartz, ProfPhD, Michelle L Bell, ProfPhD, Antonio Gasparrini, ProfPhD, Alexandra Schneider, PhD
Published 2021-04-01

Projections of excess mortality related to diurnal temperature range under climate change scenarios: a multi-country modelling study

by Whanhee Lee, PhD, Yoonhee Kim, PhD, Francesco Sera, MSc, Antonio Gasparrini, ProfPhD, Rokjin Park, ProfPhD, Hayon Michelle Choi, MSc, Kristi Prifti, MPH, Michelle L Bell, ProfPhD, Rosana Abrutzky, PhD, Yuming Guo, ProfPhD, Shilu Tong, ProfPhD, Micheline de Sousa Zanotti Stagliorio Coelho, PhD, Paulo Hilario Nascimento Saldiva, ProfPhD, Eric Lavigne, ProfPhD, Hans Orru, PhD, Ene Indermitte, PhD, Jouni J K Jaakkola, ProfPhD, Niilo R I Ryti, PhD, Mathilde Pascal, PhD, Patrick Goodman, ProfPhD, Ariana Zeka, ScD, Masahiro Hashizume, ProfPhD, Yasushi Honda, ProfPhD, Magali Hurtado Diaz, ProfPhD, Julio César Cruz, MSc, Ala Overcenco, PhD, Baltazar Nunes, ProfPhD, Joana Madureira, PhD, Noah Scovronick, PhD, Fiorella Acquaotta, PhD, Aurelio Tobias, PhD, Ana Maria Vicedo-Cabrera, PhD, Martina S Ragettli, PhD, Yue-Liang Leon Guo, ProfPhD, Bing-Yu Chen, PhD, Shanshan Li, PhD, Ben Armstrong, ProfPhD, Antonella Zanobetti, PhD, Joel Schwartz, ProfPhD, Ho Kim, ProfPhD
Published 2020-11-01