Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2

by Ieva Vasiliauskaite, Ania Owsianka, Patrick England, Abdul Ghafoor Khan, Sarah Cole, Dorothea Bankwitz, Steven K. H. Foung, Thomas Pietschmann, Joseph Marcotrigiano, Felix A. Rey, Arvind H. Patel, Thomas Krey, Peter Palese
Published 2017-05-01

Identification of a novel drug lead that inhibits HCV infection and cell-to-cell transmission by targeting the HCV E2 glycoprotein.

by Reem R Al Olaby, Laurence Cocquerel, Adam Zemla, Laure Saas, Jean Dubuisson, Jost Vielmetter, Joseph Marcotrigiano, Abdul Ghafoor Khan, Felipe Vences Catalan, Alexander L Perryman, Joel S Freundlich, Stefano Forli, Shoshana Levy, Rod Balhorn, Hassan M Azzazy
Published 2014-01-01