Bidirectional Crosstalk Between Cancer Stem Cells and Immune Cell Subsets

by Luise Müller, Antje Tunger, Antje Tunger, Ioana Plesca, Rebekka Wehner, Rebekka Wehner, Rebekka Wehner, Achim Temme, Achim Temme, Achim Temme, Dana Westphal, Friedegund Meier, Friedegund Meier, Friedegund Meier, Michael Bachmann, Michael Bachmann, Michael Bachmann, Marc Schmitz, Marc Schmitz, Marc Schmitz
Published 2020-02-01

Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs

by Michael Seifert, Gabriele Schackert, Achim Temme, Evelin Schröck, Andreas Deutsch, Barbara Klink
Published 2020-06-01

Chromosomal instability induced by increased BIRC5/Survivin levels affects tumorigenicity of glioma cells

by Marina Conde, Susanne Michen, Ralf Wiedemuth, Barbara Klink, Evelin Schröck, Gabriele Schackert, Achim Temme
Published 2017-12-01

Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment

by Antje Tunger, Maximilian Kießler, Rebekka Wehner, Achim Temme, Friedegund Meier, Michael Bachmann, Marc Schmitz
Published 2018-03-01

Tumor Evasion from T Cell Surveillance

by Katrin Töpfer, Stefanie Kempe, Nadja Müller, Marc Schmitz, Michael Bachmann, Marc Cartellieri, Gabriele Schackert, Achim Temme
Published 2011-01-01

Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

by Marc Cartellieri, Michael Bachmann, Anja Feldmann, Claudia Bippes, Slava Stamova, Rebekka Wehner, Achim Temme, Marc Schmitz
Published 2010-01-01

Glioblastoma Tissue Slice Tandem-Cultures for Quantitative Evaluation of Inhibitory Effects on Invasion and Growth

by Vasile Sidorcenco, Luisa Krahnen, Marion Schulz, Janina Remy, Donat Kögel, Achim Temme, Ute Krügel, Heike Franke, Achim Aigner
Published 2020-09-01

Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors

by Willi Jugel, Achim Aigner, Susanne Michen, Alexander Hagstotz, Alexander Ewe, Dietmar Appelhans, Gabriele Schackert, Achim Temme, Stefanie Tietze
Published 2021-05-01

The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.

by Masato Hori, Tomoharu Miki, Mayumi Okamoto, Futoshi Yazama, Hiroaki Konishi, Hiroshi Kaneko, Fumio Shimamoto, Takahide Ota, Achim Temme, Masaaki Tatsuka
Published 2013-01-01

Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity

by Anne Vehlow, Erik Klapproth, Sha Jin, Ricarda Hannen, Maria Hauswald, Jörg-Walter Bartsch, Christopher Nimsky, Achim Temme, Birgit Leitinger, Nils Cordes
Published 2019-03-01

The Influence of VE-Cadherin on Adhesion and Incorporation of Breast Cancer Cells into Vascular Endothelium

by Thomas Brock, Elisabeth Boudriot, Anke Klawitter, Marianne Großer, Trang T. P. Nguyen, Sindy Giebe, Erik Klapproth, Achim Temme, Ali El-Armouche, Georg Breier
Published 2021-06-01

tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cells.

by Mayumi Okamoto, Mamoru Fujiwara, Masato Hori, Kaoru Okada, Futoshi Yazama, Hiroaki Konishi, Yegui Xiao, Guangying Qi, Fumio Shimamoto, Takahide Ota, Achim Temme, Masaaki Tatsuka
Published 2014-09-01

Establishment and Characterisation of Heterotopic Patient-Derived Xenografts for Glioblastoma

by Sarah Meneceur, Annett Linge, Matthias Meinhardt, Sandra Hering, Steffen Löck, Rebecca Bütof, Dietmar Krex, Gabriele Schackert, Achim Temme, Michael Baumann, Mechthild Krause, Cläre von Neubeck
Published 2020-04-01

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

by Doreen Huebner, Christiane Rieger, Ralf Bergmann, Martin Ullrich, Sebastian Meister, Marieta Toma, Ralf Wiedemuth, Achim Temme, Vladimir Novotny, Manfred P. Wirth, Michael Bachmann, Jens Pietzsch, Susanne Fuessel
Published 2017-11-01

A novel ex vivo isolation and expansion procedure for chimeric antigen receptor engrafted human T cells.

by Marc Cartellieri, Stefanie Koristka, Claudia Arndt, Anja Feldmann, Slava Stamova, Malte von Bonin, Katrin Töpfer, Thomas Krüger, Mathias Geib, Irene Michalk, Achim Temme, Martin Bornhäuser, Dirk Lindemann, Gerhard Ehninger, Michael P Bachmann
Published 2014-01-01

A novel modular antigen delivery system for immuno targeting of human 6-sulfo LacNAc-positive blood dendritic cells (SlanDCs).

by Claudia C Bippes, Anja Feldmann, Slava Stamova, Marc Cartellieri, Adrian Schwarzer, Rebekka Wehner, Marc Schmitz, E Peter Rieber, Senming Zhao, Knut Schäkel, Achim Temme, R Hal Scofield, Biji T Kurien, Holger Bartsch, Michael Bachmann
Published 2011-01-01