Lysosomes and Cancer Progression: A Malignant Liaison

by Eda R. Machado, Ida Annunziata, Diantha van de Vlekkert, Gerard C. Grosveld, Alessandra d’Azzo, Alessandra d’Azzo
Published 2021-02-01

Sialylation of host proteins as targetable risk factor for COVID‐19 susceptibility and spreading: A hypothesis

by Antonella Bongiovanni, Antonella Cusimano, Ida Annunziata, Alessandra d’Azzo
Published 2021-03-01

GM1 Gangliosidosis—A Mini-Review

by Elena-Raluca Nicoli, Ida Annunziata, Alessandra d’Azzo, Alessandra d’Azzo, Frances M. Platt, Cynthia J. Tifft, Cynthia J. Tifft, Karolina M. Stepien, Karolina M. Stepien
Published 2021-09-01

Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity.

by Elizaveta Katorcha, Natallia Makarava, Regina Savtchenko, Alessandra D'Azzo, Ilia V Baskakov
Published 2014-09-01

In silico identification of new putative pathogenic variants in the NEU1 sialidase gene affecting enzyme function and subcellular localization.

by Dario Bonardi, Viola Ravasio, Giuseppe Borsani, Alessandra d'Azzo, Roberto Bresciani, Eugenio Monti, Edoardo Giacopuzzi
Published 2014-01-01

Mitochondrial alterations in dynamin 2-related centronuclear myopathy Alterações mitocondriais na miopatia centronuclear relacionadas a dinamina 2

by Edmar Zanoteli, Naja Vergani, Yvan Campos, Mariz Vainzof, Acary S.B. Oliveira, Alessandra d'Azzo
Published 2009-03-01

Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses

by Zeynep Akgoc, Miguel Sena-Esteves, Douglas R. Martin, Xianlin Han, Alessandra d'Azzo, Thomas N. Seyfried
Published 2015-05-01

Generation of human induced pluripotent stem cells (hIPSCs) from sialidosis types I and II patients with pathogenic neuraminidase 1 mutations

by Min-Joon Han, Ida Annunziata, Jason Weesner, Yvan Campos, Muneeb Salie, Carla O'Reilly, Alessandra d'Azzo
Published 2020-07-01

Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development.

by Yvan Campos, Xiaohui Qiu, Edmar Zanoteli, Simon Moshiach, Naja Vergani, Antonella Bongiovanni, A John Harris, Alessandra d'Azzo
Published 2010-03-01

Alix-mediated assembly of the actomyosin–tight junction polarity complex preserves epithelial polarity and epithelial barrier

by Yvan Campos, Xiaohui Qiu, Elida Gomero, Randall Wakefield, Linda Horner, Wojciech Brutkowski, Young-Goo Han, David Solecki, Sharon Frase, Antonella Bongiovanni, Alessandra d’Azzo
Published 2016-06-01

Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1

by Guo-Yun Chen, Nicholas K Brown, Wei Wu, Zahra Khedri, Hai Yu, Xi Chen, Diantha van de Vlekkert, Alessandra D'Azzo, Pan Zheng, Yang Liu
Published 2014-09-01

Loss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1.

by Elizaveta Katorcha, Nina Klimova, Natallia Makarava, Regina Savtchenko, Xuefang Pan, Ida Annunziata, Kohta Takahashi, Taeko Miyagi, Alexey V Pshezhetsky, Alessandra d'Azzo, Ilia V Baskakov
Published 2015-01-01

AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival.

by Rena C Baek, Marike L D Broekman, Stanley G Leroy, Laryssa A Tierney, Michael A Sandberg, Alessandra d'Azzo, Thomas N Seyfried, Miguel Sena-Esteves
Published 2010-10-01

Characterization of glycan substrates accumulating in GM1 Gangliosidosis

by Roger Lawrence, Jeremy L. Van Vleet, Linley Mangini, Adam Harris, Nathan Martin, Wyatt Clark, Sanjay Chandriani, Jonathan H. LeBowitz, Roberto Giugliani, Alessandra d'Azzo, Gouri Yogalingam, Brett E. Crawford
Published 2019-12-01

Galactosialidosis: preclinical enzyme replacement therapy in a mouse model of the disease, a proof of concept

by Jaclyn Cadaoas, Huimin Hu, Gabrielle Boyle, Elida Gomero, Rosario Mosca, Kartika Jayashankar, Mike Machado, Sean Cullen, Belle Guzman, Diantha van de Vlekkert, Ida Annunziata, Michel Vellard, Emil Kakkis, Vish Koppaka, Alessandra d’Azzo
Published 2021-03-01

Conventional and Unconventional Therapeutic Strategies for Sialidosis Type I

by Rosario Mosca, Diantha van de Vlekkert, Yvan Campos, Leigh E. Fremuth, Jaclyn Cadaoas, Vish Koppaka, Emil Kakkis, Cynthia Tifft, Camilo Toro, Simona Allievi, Cinzia Gellera, Laura Canafoglia, Gepke Visser, Ida Annunziata, Alessandra d’Azzo
Published 2020-03-01

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

by Ida Annunziata, Diantha van de Vlekkert, Elmar Wolf, David Finkelstein, Geoffrey Neale, Eda Machado, Rosario Mosca, Yvan Campos, Heather Tillman, Martine F. Roussel, Jason Andrew Weesner, Leigh Ellen Fremuth, Xiaohui Qiu, Min-Joon Han, Gerard C. Grosveld, Alessandra d’Azzo
Published 2019-08-01