Fucoidan as a Potential Therapeutic for Major Blinding Diseases—A Hypothesis

by Alexa Klettner
Published 2016-02-01

Fucoidans as Potential Therapeutics for Age-Related Macular Degeneration—Current Evidence from In Vitro Research

by Philipp Dörschmann, Alexa Klettner
Published 2020-12-01

Retinal Pigment Epithelium Expressed Toll-like Receptors and Their Potential Role in Age-Related Macular Degeneration

by Alexa Klettner, Johann Roider
Published 2021-08-01

Effects of Sulfated Fucans from <i>Laminaria hyperborea</i> Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight

by Philipp Dörschmann, Georg Kopplin, Johann Roider, Alexa Klettner
Published 2019-09-01

The Influence of Melatonin and Light on VEGF Secretion in Primary RPE Cells

by Alexa Klettner, Miriam Kampers, Daniela Töbelmann, Johann Roider, Manuela Dittmar
Published 2021-01-01

Effects of Fucoidans from Five Different Brown Algae on Oxidative Stress and VEGF Interference in Ocular Cells

by Philipp Dörschmann, Kaya Saskia Bittkau, Sandesh Neupane, Johann Roider, Susanne Alban, Alexa Klettner
Published 2019-04-01

Effects of a Newly Developed Enzyme-Assisted Extraction Method on the Biological Activities of Fucoidans in Ocular Cells

by Philipp Dörschmann, Maria Dalgaard Mikkelsen, Thuan Nguyen Thi, Johann Roider, Anne S. Meyer, Alexa Klettner
Published 2020-05-01

Fucoidan reduces secretion and expression of vascular endothelial growth factor in the retinal pigment epithelium and reduces angiogenesis in vitro.

by Michaela Dithmer, Sabine Fuchs, Yang Shi, Harald Schmidt, Elisabeth Richert, Johann Roider, Alexa Klettner
Published 2014-01-01

Comparison of the Effects of Fucoidans on the Cell Viability of Tumor and Non-Tumor Cell Lines

by Kaya Saskia Bittkau, Philipp Dörschmann, Martina Blümel, Deniz Tasdemir, Johann Roider, Alexa Klettner, Susanne Alban
Published 2019-07-01

Modulation of inflammatory processes by thermal stimulating and RPE regenerative laser therapies in age related macular degeneration mouse models

by Elisabeth Richert, Claus von der Burchard, Alexa Klettner, Philipp Arnold, Ralph Lucius, Ralf Brinkmann, Johann Roider, Jan Tode
Published 2020-09-01

Effects of Crude <i>Fucus distichus</i> Subspecies <i>evanescens</i> Fucoidan Extract on Retinal Pigment Epithelium Cells―Implications for Use in Age-Related Macular Degeneration

by Kevin Rohwer, Sandesh Neupane, Kaya Saskia Bittkau, Mayra Galarza Pérez, Philipp Dörschmann, Johann Roider, Susanne Alban, Alexa Klettner
Published 2019-09-01

Evaluation of a Brown Seaweed Extract from <i>Dictyosiphon foeniculaceus</i> as a Potential Therapeutic Agent for the Treatment of Glioblastoma and Uveal Melanoma

by Philipp Dörschmann, Christina Schmitt, Kaya Saskia Bittkau, Sandesh Neupane, Michael Synowitz, Johann Roider, Susanne Alban, Janka Held-Feindt, Alexa Klettner
Published 2020-12-01

Compromised Barrier Function in Human Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells from Type 2 Diabetic Patients

by Mostafa Kiamehr, Alexa Klettner, Elisabeth Richert, Ali Koskela, Arto Koistinen, Heli Skottman, Kai Kaarniranta, Katriina Aalto-Setälä, Kati Juuti-Uusitalo
Published 2019-08-01

Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines

by Michaela Dithmer, Anna-Maria Kirsch, Elisabeth Richert, Sabine Fuchs, Fanlu Wang, Harald Schmidt, Sarah E. Coupland, Johann Roider, Alexa Klettner
Published 2017-06-01

Pre-Analytical Parameters Affecting Vascular Endothelial Growth Factor Measurement in Plasma: Identifying Confounders.

by Johanna M Walz, Daniel Boehringer, Heidrun L Deissler, Lothar Faerber, Jens C Goepfert, Peter Heiduschka, Susannah M Kleeberger, Alexa Klettner, Tim U Krohne, Nicole Schneiderhan-Marra, Focke Ziemssen, Andreas Stahl
Published 2016-01-01