miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.

by Martin Connolly, Benjamin E Garfield, Alexi Crosby, Nick W Morrell, Stephen J Wort, Paul R Kemp
Published 2020-01-01

Targeting translational read-through of premature termination mutations in with PTC124 for pulmonary arterial hypertension

by Lu Long, Xudong Yang, Mark Southwood, Stephen Moore, Alexi Crosby, Paul D. Upton, Benjamin J. Dunmore, Nicholas W. Morrell
Published 2020-07-01

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in -deficient mice

by Alexi Crosby, Mark R. Toshner, Mark R. Southwood, Elaine Soon, Benjamin J. Dunmore, Emily Groves, Stephen Moore, Penny Wright, Katrin Ottersbach, Cavan Bennett, Jose Guerrero, Cedric Ghevaert, Nicholas W. Morrell
Published 2018-09-01

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

by Liam A. Hurst, Benjamin J. Dunmore, Lu Long, Alexi Crosby, Rafia Al-Lamki, John Deighton, Mark Southwood, Xudong Yang, Marko Z. Nikolic, Blanca Herrera, Gareth J. Inman, John R. Bradley, Amer A. Rana, Paul D. Upton, Nicholas W. Morrell
Published 2017-01-01