Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation.

by Alice C-H Chen, Megan L Martin, Rohan Lourie, Geraint B Rogers, Lucy D Burr, Sumaira Z Hasnain, Simon D Bowler, Michael A McGuckin, David J Serisier
Published 2015-01-01

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa.

by Lucy D Burr, Geraint B Rogers, Alice C-H Chen, Steven L Taylor, Simon D Bowler, Rebecca L Keating, Megan L Martin, Sumaira Z Hasnain, Michael A McGuckin
Published 2018-01-01

Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β

by Alice C-H. Chen, Yang Xi, Melanie Carroll, Helen L. Petsky, Samantha J. Gardiner, Susan J. Pizzutto, Stephanie T. Yerkovich, Katherine J. Baines, Peter G. Gibson, Sandra Hodge, Ian B. Masters, Helen M. Buntain, Anne B. Chang, John W. Upham
Published 2017-10-01

Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis

by Alice C-H. Chen, Hai B. Tran, Yang Xi, Stephanie T. Yerkovich, Katherine J. Baines, Susan J. Pizzutto, Melanie Carroll, Avril A.B. Robertson, Matthew A. Cooper, Kate Schroder, Jodie L. Simpson, Peter G. Gibson, Greg Hodge, Ian B. Masters, Helen M. Buntain, Helen L. Petsky, Samantha J. Prime, Anne B. Chang, Sandra Hodge, John W. Upham
Published 2018-03-01