Adaptor CAR Platforms—Next Generation of T Cell-Based Cancer Immunotherapy

by Claudia Arndt, Frederick Fasslrinner, Liliana R. Loureiro, Stefanie Koristka, Anja Feldmann, Michael Bachmann
Published 2020-05-01

Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

by Marc Cartellieri, Michael Bachmann, Anja Feldmann, Claudia Bippes, Slava Stamova, Rebekka Wehner, Achim Temme, Marc Schmitz
Published 2010-01-01

Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8.

by Irene Michalk, Anja Feldmann, Stefanie Koristka, Claudia Arndt, Marc Cartellieri, Armin Ehninger, Gerhard Ehninger, Michael P Bachmann
Published 2014-01-01

T cells engrafted with a UniCAR 28/z outperform UniCAR BB/z-transduced T cells in the face of regulatory T cell-mediated immunosuppression

by Alexandra Kegler, Stefanie Koristka, Ralf Bergmann, Nicole Berndt, Claudia Arndt, Anja Feldmann, Anja Hoffmann, Martin Bornhäuser, Marc Schmitz, Michael P. Bachmann
Published 2019-09-01

Cancer Immunotherapy by Retargeting of Immune Effector Cells via Recombinant Bispecific Antibody Constructs

by Slava Stamova, Stefanie Koristka, Juliane Keil, Claudia Arndt, Anja Feldmann, Irene Michalk, Holger Bartsch, Claudia C. Bippes, Marc Schmitz, Marc Cartellieri, Michael Bachmann
Published 2012-07-01

Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers

by Liliana R. Loureiro, Anja Feldmann, Ralf Bergmann, Stefanie Koristka, Nicole Berndt, Domokos Máthé, Nikolett Hegedüs, Krisztián Szigeti, Paula A. Videira, Michael Bachmann, Claudia Arndt
Published 2020-05-01

Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia

by Simon Loff, Josephine Dietrich, Jan-Erik Meyer, Julia Riewaldt, Johannes Spehr, Malte von Bonin, Cordula Gründer, Mridula Swayampakula, Kristin Franke, Anja Feldmann, Michael Bachmann, Gerhard Ehninger, Armin Ehninger, Marc Cartellieri
Published 2020-06-01

Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

by Anja Feldmann, Anja Hoffmann, Ralf Bergmann, Stefanie Koristka, Nicole Berndt, Claudia Arndt, Liliana Rodrigues Loureiro, Enrico Kittel-Boselli, Nicola Mitwasi, Alexandra Kegler, Chris Lamprecht, Karla Elizabeth González Soto, Michael Bachmann
Published 2020-01-01

A novel ex vivo isolation and expansion procedure for chimeric antigen receptor engrafted human T cells.

by Marc Cartellieri, Stefanie Koristka, Claudia Arndt, Anja Feldmann, Slava Stamova, Malte von Bonin, Katrin Töpfer, Thomas Krüger, Mathias Geib, Irene Michalk, Achim Temme, Martin Bornhäuser, Dirk Lindemann, Gerhard Ehninger, Michael P Bachmann
Published 2014-01-01

A novel modular antigen delivery system for immuno targeting of human 6-sulfo LacNAc-positive blood dendritic cells (SlanDCs).

by Claudia C Bippes, Anja Feldmann, Slava Stamova, Marc Cartellieri, Adrian Schwarzer, Rebekka Wehner, Marc Schmitz, E Peter Rieber, Senming Zhao, Knut Schäkel, Achim Temme, R Hal Scofield, Biji T Kurien, Holger Bartsch, Michael Bachmann
Published 2011-01-01

Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model

by Elham Pishali Bejestani, Marc Cartellieri, Ralf Bergmann, Armin Ehninger, Simon Loff, Michael Kramer, Johannes Spehr, Antje Dietrich, Anja Feldmann, Susann Albert, Martin Wermke, Michael Baumann, Mechthild Krause, Martin Bornhäuser, Gerhard Ehninger, Michael Bachmann, Malte von Bonin
Published 2017-10-01

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

by Susann Albert, Claudia Arndt, Anja Feldmann, Ralf Bergmann, Dominik Bachmann, Stefanie Koristka, Florian Ludwig, Pauline Ziller-Walter, Alexandra Kegler, Sebastian Gärtner, Marc Schmitz, Armin Ehninger, Marc Cartellieri, Gerhard Ehninger, Hans-Jürgen Pietzsch, Jens Pietzsch, Jörg Steinbach, Michael Bachmann
Published 2017-04-01

A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

by Claudia Arndt, Anja Feldmann, Stefanie Koristka, Martin Schäfer, Ralf Bergmann, Nicola Mitwasi, Nicole Berndt, Dominik Bachmann, Alexandra Kegler, Marc Schmitz, Edinson Puentes-Cala, Javier Andrés Soto, Gerhard Ehninger, Jens Pietzsch, Christos Liolios, Gerd Wunderlich, Jörg Kotzerke, Klaus Kopka, Michael Bachmann
Published 2019-11-01

UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

by Claudia Arndt, Liliana R. Loureiro, Anja Feldmann, Justyna Jureczek, Ralf Bergmann, Domokos Máthé, Nikolett Hegedüs, Nicole Berndt, Stefanie Koristka, Nicola Mitwasi, Frederick Fasslrinner, Chris Lamprecht, Alexandra Kegler, Anja Hoffmann, Tabea Bartsch, Ayşe Sedef Köseer, Gary Egan, Marc Schmitz, Vaclav Hořejší, Mechthild Krause, Anna Dubrovska, Michael Bachmann
Published 2020-01-01

T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation

by Michael P. Bachmann, Tabea Bartsch, Claudia C. Bippes, Dominik Bachmann, Edinson Puentes-Cala, Jennifer Bachmann, Holger Bartsch, Claudia Arndt, Stefanie Koristka, Liliana R. Loureiro, Alexandra Kegler, Markus Laube, Joanne K. Gross, Tim Gross, Biji T. Kurien, R. Hal Scofield, A. Darise Farris, Judith A. James, Marc Schmitz, Anja Feldmann
Published 2021-01-01

And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling

by Nicole Berndt, Claudia C. Bippes, Irene Michalk, Tabea Bartsch, Claudia Arndt, Edinson Puentes-Cala, Javier Andrés Soto, Liliana R. Loureiro, Alexandra Kegler, Dominik Bachmann, Joanne K. Gross, Tim Gross, Biji T. Kurien, R. Hal Scofield, A. Darise Farris, Judith A. James, Ralf Bergmann, Marc Schmitz, Anja Feldmann, Michael P. Bachmann
Published 2021-09-01

Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is able to form Dimers and Oligomers in a Redox Dependent Manner

by Nicole Berndt, Claudia C. Bippes, Irene Michalk, Dominik Bachmann, Jennifer Bachmann, Edinson Puentes-Cala, Tabea Bartsch, Liliana R. Loureiro, Alexandra Kegler, Ralf Bergmann, Joanne K. Gross, Tim Gross, Biji T. Kurien, R. Hal Scofield, A. Darise Farris, Judith A. James, Marc Schmitz, Karim Fahmy, Anja Feldmann, Claudia Arndt, Michael P. Bachmann
Published 2021-03-01