Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination

by Carolyn H. Rogers, Olga Mielczarek, Anne E. Corcoran
Published 2021-02-01

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination

by Louise S. Matheson, Daniel J. Bolland, Peter Chovanec, Felix Krueger, Simon Andrews, Hashem Koohy, Anne E. Corcoran
Published 2017-11-01

IL-7R signaling activates widespread VH and DH gene usage to drive antibody diversity in bone marrow B cells

by Amanda Baizan-Edge, Bryony A. Stubbs, Michael J.T. Stubbington, Daniel J. Bolland, Kristina Tabbada, Simon Andrews, Anne E. Corcoran
Published 2021-07-01

Myc dynamically and preferentially relocates to a transcription factory occupied by Igh.

by Cameron S Osborne, Lyubomira Chakalova, Jennifer A Mitchell, Alice Horton, Andrew L Wood, Daniel J Bolland, Anne E Corcoran, Peter Fraser
Published 2007-08-01

Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states

by Peter Chovanec, Amanda J. Collier, Christel Krueger, Csilla Várnai, Claudia I. Semprich, Stefan Schoenfelder, Anne E. Corcoran, Peter J. Rugg-Gunn
Published 2021-04-01

Clonally stable Vκ allelic choice instructs Igκ repertoire

by Rena Levin-Klein, Shira Fraenkel, Michal Lichtenstein, Louise S. Matheson, Osnat Bartok, Yuval Nevo, Sebastian Kadener, Anne E. Corcoran, Howard Cedar, Yehudit Bergman
Published 2017-05-01

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination

by Daniel J. Bolland, Hashem Koohy, Andrew L. Wood, Louise S. Matheson, Felix Krueger, Michael J.T. Stubbington, Amanda Baizan-Edge, Peter Chovanec, Bryony A. Stubbs, Kristina Tabbada, Simon R. Andrews, Mikhail Spivakov, Anne E. Corcoran
Published 2016-06-01

Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

by Hashem Koohy, Daniel J. Bolland, Louise S. Matheson, Stefan Schoenfelder, Claudia Stellato, Andrew Dimond, Csilla Várnai, Peter Chovanec, Tamara Chessa, Jeremy Denizot, Raquel Manzano Garcia, Steven W. Wingett, Paula Freire-Pritchett, Takashi Nagano, Phillip Hawkins, Len Stephens, Sarah Elderkin, Mikhail Spivakov, Peter Fraser, Anne E. Corcoran, Patrick D. Varga-Weisz
Published 2018-09-01