Anti-Gb3 monoclonal antibody inhibits angiogenesis and tumor development.

by Ariane Desselle, Tanguy Chaumette, Marie-Hélène Gaugler, Denis Cochonneau, Julien Fleurence, Nolwenn Dubois, Philippe Hulin, Jacques Aubry, Stéphane Birklé, François Paris
Published 2012-01-01

212 CLEC-1 is a novel myeloid immune checkpoint for cancer immunotherapy limiting tumor cells phagocytosis and synergizing with tumor-targeted antibodies

by Vanessa Gauttier, Marion Drouin, Sabrina Pengam, Javier Saenz, Bérangère Evrard, Caroline Mary, Géraldine Teppaz, Ariane Desselle, Virginie Thépénier, Emmanuelle Wilhelm, Elise Chiffoleau, Nicolas Poirier
Published 2020-11-01

A monoclonal antibody to O-acetyl-GD2 ganglioside and not to GD2 shows potent anti-tumor activity without peripheral nervous system cross-reactivity.

by Nidia Alvarez-Rueda, Ariane Desselle, Denis Cochonneau, Tanguy Chaumette, Béatrice Clemenceau, Stéphanie Leprieur, Gwenola Bougras, Stéphane Supiot, Jean-Marie Mussini, Jacques Barbet, Julie Saba, François Paris, Jacques Aubry, Stéphane Birklé
Published 2011-01-01