Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies

by Jenni Karttunen, Mette Heiskanen, Anssi Lipponen, David Poulsen, Asla Pitkänen
Published 2019-03-01

Epilepsy biomarkers – Toward etiology and pathology specificity

by Asla Pitkänen, Xavier Ekolle Ndode-Ekane, Niina Lapinlampi, Noora Puhakka
Published 2019-03-01

MRS Reveals Chronic Inflammation in T2w MRI-Negative Perilesional Cortex – A 6-Months Multimodal Imaging Follow-Up Study

by Amna Yasmin, Asla Pitkänen, Kimmo Jokivarsi, Pekka Poutiainen, Olli Gröhn, Riikka Immonen
Published 2019-08-01

Big data sharing and analysis to advance research in post-traumatic epilepsy

by Dominique Duncan, Paul Vespa, Asla Pitkänen, Adebayo Braimah, Niina Lapinlampi, Arthur W. Toga
Published 2019-03-01

Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse

by Terhi J. Pirttilä, Katarzyna Lukasiuk, Katarina Håkansson, Anders Grubb, Magnus Abrahamson, Asla Pitkänen
Published 2005-11-01

Chronically dysregulated NOTCH1 interactome in the dentate gyrus after traumatic brain injury.

by Noora Puhakka, Anna Maria Bot, Niina Vuokila, Konrad Jozef Debski, Katarzyna Lukasiuk, Asla Pitkänen
Published 2017-01-01

Chronic Regulation of miR-124-3p in the Perilesional Cortex after Experimental and Human TBI

by Niina Vuokila, Eleonora Aronica, Anatoly Korotkov, Erwin Alexander van Vliet, Salma Nuzhat, Noora Puhakka, Asla Pitkänen
Published 2020-03-01

Reorganization of Thalamic Inputs to Lesioned Cortex Following Experimental Traumatic Brain Injury

by Xavier Ekolle Ndode-Ekane, Maria del Mar Puigferrat Pérez, Rossella Di Sapia, Niina Lapinlampi, Asla Pitkänen
Published 2021-06-01

Plasma miR-9-3p and miR-136-3p as Potential Novel Diagnostic Biomarkers for Experimental and Human Mild Traumatic Brain Injury

by Shalini Das Gupta, Robert Ciszek, Mette Heiskanen, Niina Lapinlampi, Janne Kukkonen, Ville Leinonen, Noora Puhakka, Asla Pitkänen
Published 2021-02-01

Corrigendum to “Urokinase-type plasminogen activator regulates neurodegeneration and neurogenesis but not vascular changes in the mouse hippocampus after status epilepticus” [Neuro...

by Laura Lahtinen, Xavier Ekolle Ndode-Ekane, Filip Barinka, Yumiko Akamine, Mohammed Hossein Esmaeili, Jukka Rantala, Asla Pitkänen
Published 2011-01-01

Urokinase-type plasminogen activator regulates neurodegeneration and neurogenesis but not vascular changes in the mouse hippocampus after status epilepticus

by Laura Lahtinen, Xavier Ekolle Ndode-Ekane, Filip Barinka, Yumiko Akamine, Mohammed Hossein Esmaeili, Jukka Rantala, Asla Pitkänen
Published 2010-03-01

Kainate receptors regulate development of glutamatergic synaptic circuitry in the rodent amygdala

by Maria Ryazantseva, Jonas Englund, Alexandra Shintyapina, Johanna Huupponen, Vasilii Shteinikov, Asla Pitkänen, Juha M Partanen, Sari E Lauri
Published 2020-03-01

Gender issues in antiepileptogenic treatments

by Asla Pitkänen, Noora Huusko, Xavier Ekolle Ndode-Ekane, Jenni Kyyriäinen, Anssi Lipponen, Anu Lipsanen, Alejandra Sierra, Tamuna Bolkvadze
Published 2014-12-01

Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs

by Jenni Karttunen, Mette Heiskanen, Vicente Navarro-Ferrandis, Shalini Das Gupta, Anssi Lipponen, Noora Puhakka, Kirsi Rilla, Arto Koistinen, Asla Pitkänen
Published 2019-12-01

Analytic Tools for Post-traumatic Epileptogenesis Biomarker Search in Multimodal Dataset of an Animal Model and Human Patients

by Dominique Duncan, Giuseppe Barisano, Ryan Cabeen, Farshid Sepehrband, Rachael Garner, Adebayo Braimah, Paul Vespa, Asla Pitkänen, Meng Law, Arthur W. Toga
Published 2018-12-01

Decreased resting functional connectivity after traumatic brain injury in the rat.

by Asht Mangal Mishra, Xiaoxiao Bai, Basavaraju G Sanganahalli, Stephen G Waxman, Olena Shatillo, Olli Grohn, Fahmeed Hyder, Asla Pitkänen, Hal Blumenfeld
Published 2014-01-01

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

by Anssi Lipponen, Assam El-Osta, Antony Kaspi, Mark Ziemann, Ishant Khurana, Harikrishnan KN, Vicente Navarro-Ferrandis, Noora Puhakka, Jussi Paananen, Asla Pitkänen
Published 2018-02-01

Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury

by Erwin A. van Vliet, Xavier Ekolle Ndode-Ekane, Lauri J. Lehto, Jan A. Gorter, Pedro Andrade, Eleonora Aronica, Olli Gröhn, Asla Pitkänen
Published 2020-11-01

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury—Lessons Learned

by Anssi Lipponen, Teemu Natunen, Mika Hujo, Robert Ciszek, Elina Hämäläinen, Jussi Tohka, Mikko Hiltunen, Jussi Paananen, David Poulsen, Emilia Kansanen, Xavier Ekolle Ndode-Ekane, Anna-Liisa Levonen, Asla Pitkänen
Published 2019-10-01