Structural and biophysical characterization of the nucleosome-binding PZP domain

by Brianna J. Klein, Khan L. Cox, Suk Min Jang, Rohit K. Singh, Jacques Côté, Michael G. Poirier, Tatiana G. Kutateladze
Published 2021-06-01

E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair

by Swarnalatha Manickavinayaham, Renier Vélez-Cruz, Anup K. Biswas, Ella Bedford, Brianna J. Klein, Tatiana G. Kutateladze, Bin Liu, Mark T. Bedford, David G. Johnson
Published 2019-10-01

G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression

by Xi Zhang, Danni Peng, Yuanxin Xi, Chao Yuan, Cari A. Sagum, Brianna J. Klein, Kaori Tanaka, Hong Wen, Tatiana G. Kutateladze, Wei Li, Mark T. Bedford, Xiaobing Shi
Published 2016-03-01

Molecular mechanism of the MORC4 ATPase activation

by Adam H. Tencer, Khan L. Cox, Gregory M. Wright, Yi Zhang, Christopher J. Petell, Brianna J. Klein, Brian D. Strahl, Joshua C. Black, Michael G. Poirier, Tatiana G. Kutateladze
Published 2020-10-01

PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation

by Brianna J. Klein, Xiaoyan Wang, Gaofeng Cui, Chao Yuan, Maria Victoria Botuyan, Kevin Lin, Yue Lu, Xiaolu Wang, Yue Zhao, Christiane J. Bruns, Georges Mer, Xiaobing Shi, Tatiana G. Kutateladze
Published 2016-10-01

Characterization of histone acylations links chromatin modifications with metabolism

by Johayra Simithy, Simone Sidoli, Zuo-Fei Yuan, Mariel Coradin, Natarajan V. Bhanu, Dylan M. Marchione, Brianna J. Klein, Gleb A. Bazilevsky, Cheryl E. McCullough, Robert S. Magin, Tatiana G. Kutateladze, Nathaniel W. Snyder, Ronen Marmorstein, Benjamin A. Garcia
Published 2017-10-01

Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain

by Brianna J. Klein, Kendra R. Vann, Forest H. Andrews, Wesley W. Wang, Jibo Zhang, Yi Zhang, Anastasia A. Beloglazkina, Wenyi Mi, Yuanyuan Li, Haitao Li, Xiaobing Shi, Andrei G. Kutateladze, Brian D. Strahl, Wenshe R. Liu, Tatiana G. Kutateladze
Published 2018-11-01

The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations

by Brianna J. Klein, Anagha Deshpande, Khan L. Cox, Fan Xuan, Mohamad Zandian, Karina Barbosa, Sujita Khanal, Qiong Tong, Yi Zhang, Pan Zhang, Amit Sinha, Stefan K. Bohlander, Xiaobing Shi, Hong Wen, Michael G. Poirier, Aniruddha J. Deshpande, Tatiana G. Kutateladze
Published 2021-07-01

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF

by Yi Zhang, Younghoon Jang, Ji-Eun Lee, JaeWoo Ahn, Longxia Xu, Michael R. Holden, Evan M. Cornett, Krzysztof Krajewski, Brianna J. Klein, Shu-Ping Wang, Yali Dou, Robert G. Roeder, Brian D. Strahl, Scott B. Rothbart, Xiaobing Shi, Kai Ge, Tatiana G. Kutateladze
Published 2019-05-01

The Histone-H3K4-Specific Demethylase KDM5B Binds to Its Substrate and Product through Distinct PHD Fingers

by Brianna J. Klein, Lianhua Piao, Yuanxin Xi, Hector Rincon-Arano, Scott B. Rothbart, Danni Peng, Hong Wen, Connie Larson, Xi Zhang, Xia Zheng, Michael A. Cortazar, Pedro V. Peña, Anthony Mangan, David L. Bentley, Brian D. Strahl, Mark Groudine, Wei Li, Xiaobing Shi, Tatiana G. Kutateladze
Published 2014-01-01

Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation

by Brianna J. Klein, Suk Min Jang, Catherine Lachance, Wenyi Mi, Jie Lyu, Shun Sakuraba, Krzysztof Krajewski, Wesley W. Wang, Simone Sidoli, Jiuyang Liu, Yi Zhang, Xiaolu Wang, Becka M. Warfield, Andrew J. Kueh, Anne K. Voss, Tim Thomas, Benjamin A. Garcia, Wenshe R. Liu, Brian D. Strahl, Hidetoshi Kono, Wei Li, Xiaobing Shi, Jacques Côté, Tatiana G. Kutateladze
Published 2019-10-01