ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP

by Muranen, Taru, Selfors, Laura M., Hwang, Julie, Gallegos, Lisa L., Coloff, Jonathan L., Mills, Gordon B., Brugge, Joan S., Thoreen, Carson C, Kang, Seong-Cheol, Sabatini, David
Published 2018

Differential Remodeling of Actin Cytoskeleton Architecture by Profilin Isoforms Leads to Distinct Effects on Cell Migration and Invasion

by Mouneimne, Ghassan, Hansen, Scott D, Selfors, Laura M, Petrak, Lara, Hickey, Michele M., Gallegos, Lisa L, Simpson, Kaylene J, Lim, James, Gertler, Frank, Hartwig, John H, Mullins, R. Dyche, Brugge, Joan S.
Published 2014

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

by Hung, Yin P, Teragawa, Carolyn, Kosaisawe, Nont, Gillies, Taryn E, Pargett, Michael, Minguet, Marta, Distor, Kevin, Rocha-Gregg, Briana L, Coloff, Jonathan L, Yellen, Gary, Brugge, Joan S, Albeck, John G, Keibler, Mark Andrew, Stephanopoulos, Gregory
Published 2018

MYC regulation of a "poor-prognosis" metastatic cancer cell state

by Mesirov, Jill P., Wolfer, Anita, Wittner, Ben S., Irimia, Daniel, Flavin, Richard J., Lupien, Mathieu, Gunawardane, Ruwanthi N., Meyer, Clifford A., Lightcap, Eric S., Tamayo, Pablo, Liu, X. Shirley, Shioda, Toshi, Toner, Mehmet, Loda, Massimo, Brown, Myles, Brugge, Joan S., Ramaswamy, Sridhar
Published 2014

Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues

by Wang, Yu, Woehrstein, Johannes B., Donoghue, Noah, Dai, Mingjie, Avendaño, Maier S., Schackmann, Ron C. J., Zoeller, Jason J., Wang, Shan Shan H., Tillberg, Paul W., Park, Demian, Lapan, Sylvain W., Boyden, Edward, Brugge, Joan S., Kaeser, Pascal S., Church, George M., Agasti, Sarit S., Jungmann, Ralf, Yin, Peng
Published 2020

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

by Locasale, Jason W., Grassian, Alexandra R., Melman, Tamar, Lyssiotis, Costas A., Mattaini, Katherine Ruth, Bass, Adam J., Heffron, Gregory J., Metallo, Christian M., Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T., Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I., Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H., Meyerson, Matthew L., Richardson, Andrea L., Chin, Lynda, Wagner, Gerhard, Asara, John M., Brugge, Joan S., Cantley, Lewis C., Vander Heiden, Matthew G.
Published 2013