Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing.

by Victoria K Hill, Jung-Sik Kim, C David James, Todd Waldman
Published 2017-01-01

Challenges in EGFRvIII detection in head and neck squamous cell carcinoma.

by Sarah E Wheeler, Ann Marie Egloff, Lin Wang, C David James, Peter S Hammerman, Jennifer R Grandis
Published 2015-01-01

Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging

by Adam W. Autry, Rintaro Hashizume, C. David James, Peder E. Z. Larson, Daniel B. Vigneron, Ilwoo Park
Published 2018-01-01

Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells

by Ravi D. Rao, Ann C. Mladek, Jeffrey D. Lamont, Jennie M. Goble, Charles Erlichman, C. David James, Jann N. Sarkaria
Published 2005-10-01

Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma

by Tina Y. Huang, Andrea Piunti, Rishi R. Lulla, Jin Qi, Craig M. Horbinski, Tadanori Tomita, C. David James, Ali Shilatifard, Amanda M. Saratsis
Published 2017-04-01

Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.

by Jane R Engler, Aaron E Robinson, Ivan Smirnov, J Graeme Hodgson, Mitchel S Berger, Nalin Gupta, C David James, Annette Molinaro, Joanna J Phillips
Published 2012-01-01

Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models

by Andrey Ugolkov, Wenan Qiang, Gennadiy Bondarenko, Daniel Procissi, Irina Gaisina, C. David James, James Chandler, Alan Kozikowski, Hendra Gunosewoyo, Thomas O'Halloran, Jeffrey Raizer, Andrew P. Mazar
Published 2017-08-01

A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways

by Tianzhi Huang, Angel A. Alvarez, Rajendra P. Pangeni, Craig M. Horbinski, Songjian Lu, Sung-Hak Kim, C. David James, Jeffery J. Raizer, John A. Kessler, Cameron W. Brenann, Erik P. Sulman, Gaetano Finocchiaro, Ming Tan, Ryo Nishikawa, Xinghua Lu, Ichiro Nakano, Bo Hu, Shi-Yuan Cheng
Published 2016-10-01

A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2

by Jing Zhou, An-Chi Tien, John A. Alberta, Scott B. Ficarro, Amelie Griveau, Yu Sun, Janhavee S. Deshpande, Joseph D. Card, Meghan Morgan-Smith, Wojciech Michowski, Rintaro Hashizume, C. David James, Keith L. Ligon, William D. Snider, Peter Sicinski, Jarrod A. Marto, David H. Rowitch, Charles D. Stiles
Published 2017-03-01

Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

by Andrea E. Calvert, Alexandra Chalastanis, Yongfei Wu, Lisa A. Hurley, Fotini M. Kouri, Yingtao Bi, Maureen Kachman, Jasmine L. May, Elizabeth Bartom, Youjia Hua, Rama K. Mishra, Gary E. Schiltz, Oleksii Dubrovskyi, Andrew P. Mazar, Marcus E. Peter, Hongwu Zheng, C. David James, Charles F. Burant, Navdeep S. Chandel, Ramana V. Davuluri, Craig Horbinski, Alexander H. Stegh
Published 2017-05-01