Overcoming the limitations of locally administered oncolytic virotherapy

by JinWoo Hong, Chae-Ok Yun
Published 2019-07-01

Telomere Gene Therapy: Polarizing Therapeutic Goals for Treatment of Various Diseases

by JinWoo Hong, Chae-Ok Yun
Published 2019-04-01

Regulatory T Cells Induce Metastasis by Activating Tgf-Β and Enhancing the Epithelial–Mesenchymal Transition

by Eonju Oh, JinWoo Hong, Chae-Ok Yun
Published 2019-11-01

Oncolytic Viruses and Immune Checkpoint Inhibitors: Preclinical Developments to Clinical Trials

by June Kyu Hwang, JinWoo Hong, Chae-Ok Yun
Published 2020-11-01

Optimising Hydrogel Release Profiles for Viro-Immunotherapy Using Oncolytic Adenovirus Expressing IL-12 and GM-CSF with Immature Dendritic Cells

by Adrianne L. Jenner, Federico Frascoli, Chae-Ok Yun, Peter S. Kim
Published 2020-04-01

A hypoxia- and telomerase-responsive oncolytic adenovirus expressing secretable trimeric TRAIL triggers tumour-specific apoptosis and promotes viral dispersion in TRAIL-resistant g...

by Eonju Oh, JinWoo Hong, Oh-Joon Kwon, Chae-Ok Yun
Published 2018-01-01

Oncolytic adenovirus expressing IL-23 and p35 elicits IFN-γ- and TNF-α-co-producing T cell-mediated antitumor immunity.

by Il-Kyu Choi, Yan Li, Eonju Oh, Jaesung Kim, Chae-Ok Yun
Published 2013-01-01

Modelling combined virotherapy and immunotherapy: strengthening the antitumour immune response mediated by IL-12 and GM-CSF expression

by Adrianne L. Jenner, Chae-Ok Yun, Arum Yoon, Adelle C. F. Coster, Peter S. Kim
Published 2018-06-01

Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids

by Won Jai Lee, Hyo Min Ahn, Youjin Na, Renu Wadhwa, JinWoo Hong, Chae-Ok Yun
Published 2017-10-01

A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer.

by Jung-Sun Lee, Man-Wook Hur, Seong Kyung Lee, Won-Il Choi, Young-Guen Kwon, Chae-Ok Yun
Published 2012-01-01

Bioinformatics and Molecular Insights to Anti-Metastasis Activity of Triethylene Glycol Derivatives

by Vidhi Malik, Sukant Garg, Sajal Afzal, Jaspreet Kaur Dhanjal, Chae-Ok Yun, Sunil C. Kaul, Durai Sundar, Renu Wadhwa
Published 2020-07-01

Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apopto...

by Yeo Reum Jeon, Hyun Roh, Ji Hyuk Jung, Hyo Min Ahn, Ju Hee Lee, Chae-Ok Yun, Won Jai Lee
Published 2019-08-01

CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target

by Rajkumar S. Kalra, Anupama Chaudhary, A-Rum Yoon, Priyanshu Bhargava, Amr Omar, Sukant Garg, Chae-Ok Yun, Sunil C. Kaul, Renu Wadhwa
Published 2018-05-01

Epithelial-mesenchymal transition in keloid tissue

by Chae-Eun Yang, Seung Jin Moon, Soo Jung Kim, Ju Hee Lee, Chae-Ok Yun, Dae Hyun Lew, Won Jai Lee
Published 2018-11-01

Molecular dynamics simulations and experimental studies reveal differential permeability of withaferin-A and withanone across the model cell membrane

by Renu Wadhwa, Neetu Singh Yadav, Shashank P. Katiyar, Tomoko Yaguchi, Chohee Lee, Hyomin Ahn, Chae-Ok Yun, Sunil C. Kaul, Durai Sundar
Published 2021-01-01

Sustained Release of Decoy Wnt Receptor (sLRP6E1E2)-Expressing Adenovirus Using Gel-Encapsulation for Scar Remodeling in Pig Model

by Chae-Eun Yang, Sewoon Choi, Ju Hee Lee, Eun Hye Kang, Hyo Min Ahn, Tai Suk Roh, Chae-Ok Yun, Won Jai Lee
Published 2020-03-01

Immunogenic Cell Death Inducing Fluorinated Mitochondria‐Disrupting Helical Polypeptide Synergizes with PD‐L1 Immune Checkpoint Blockade

by Seong Dong Jeong, Bo‐Kyeong Jung, Hyo Min Ahn, DaeYong Lee, JongHoon Ha, Ilkoo Noh, Chae‐Ok Yun, Yeu‐Chun Kim
Published 2021-04-01

Relaxin-expressing oncolytic adenovirus induces remodeling of physical and immunological aspects of cold tumor to potentiate PD-1 blockade

by Bo-Kyeong Jung, Hae Young Ko, Hyunji Kang, JinWoo Hong, Hyo Min Ahn, Youjin Na, Hyeongi Kim, Jin Su Kim, Chae-Ok Yun
Published 2020-07-01

Identification and Functional Characterization of Anti-metastasis and Anti-angiogenic Activities of Triethylene Glycol Derivatives

by Eonju Oh, Sukant Garg, Sukant Garg, Ye Liu, Sajal Afzal, Sajal Afzal, Ran Gao, Chae-Ok Yun, Sunil C. Kaul, Renu Wadhwa, Renu Wadhwa
Published 2018-11-01

Inhibition of Wnt signaling pathway suppresses radiation-induced dermal fibrosis

by Dong Won Lee, Won Jai Lee, Jaeho Cho, Chae-Ok Yun, Hyun Roh, Hsien Pin Chang, Tai Suk Roh, Ju Hee Lee, Dae Hyun Lew
Published 2020-08-01