Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes

by Stetson Thacker, Charis Eng
Published 2021-06-01

AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma.

by Kristi L Bennett, Todd Romigh, Charis Eng
Published 2009-09-01

Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort.

by Mohammed S Orloff, Li Zhang, Gurkan Bebek, Charis Eng
Published 2012-01-01

Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity

by Nick Sarn, Stetson Thacker, Hyunpil Lee, Charis Eng
Published 2021-06-01

The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane

by Hyunbum Jang, Iris Nira Smith, Charis Eng, Ruth Nussinov
Published 2021-05-01

Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors

by Sara Akhavanfard, Roshan Padmanabhan, Lamis Yehia, Feixiong Cheng, Charis Eng
Published 2020-05-01

Genome-wide tracts of homozygosity and exome analyses reveal repetitive elements with Barrets esophagus/esophageal adenocarcinoma risk

by Visanu Wanchai, Jing Jin, Emine Bircan, Charis Eng, Mohammed Orloff
Published 2019-03-01

Formative Evaluation of Clinician Experience with Integrating Family History-Based Clinical Decision Support into Clinical Practice

by Megan Doerr, Emily Edelman, Emily Gabitzsch, Charis Eng, Kathryn Teng
Published 2014-03-01

Non-canonical role of wild-type SEC23B in the cellular stress response pathway

by Lamis Yehia, Darren Liu, Shuai Fu, Pranav Iyer, Charis Eng
Published 2021-03-01

Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.

by Yongzhong Zhao, Michael Marotta, Evan E Eichler, Charis Eng, Hisashi Tanaka
Published 2009-05-01

cgaTOH: extended approach for identifying tracts of homozygosity.

by Li Zhang, Mohammed S Orloff, Sean Reber, Shengchao Li, Ye Zhao, Charis Eng
Published 2013-01-01

Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression

by Ritika Jaini, Matthew R. Wolf, Qi Yu, Alexander T. King, Thomas W. Frazier, Charis Eng
Published 2021-06-01

Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation

by Shin Chung Kang, Ritika Jaini, Masahiro Hitomi, Hyunpil Lee, Nick Sarn, Stetson Thacker, Charis Eng
Published 2020-06-01

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.

by Chuang Liu, Junfei Zhao, Weiqiang Lu, Yao Dai, Jennifer Hockings, Yadi Zhou, Ruth Nussinov, Charis Eng, Feixiong Cheng
Published 2020-02-01

My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype

by Yadi Zhou, Junfei Zhao, Jiansong Fang, William Martin, Lang Li, Ruth Nussinov, Timothy A. Chan, Charis Eng, Feixiong Cheng
Published 2021-01-01

Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations.

by Lamis Yehia, Ying Ni, Kaitlin Sesock, Farshad Niazi, Benjamin Fletcher, Hannah Jin Lian Chen, Thomas LaFramboise, Charis Eng
Published 2018-04-01

Psychiatric Characteristics Across Individuals With PTEN Mutations

by Morgan Steele, Mirko Uljarević, Mirko Uljarević, Gaëlle Rached, Thomas W. Frazier, Thomas W. Frazier, Jennifer M. Phillips, Robin A. Libove, Robyn M. Busch, Robyn M. Busch, Patricia Klaas, Julian A. Martinez-Agosto, Siddharth Srivastava, Charis Eng, Charis Eng, Mustafa Sahin, Antonio Y. Hardan
Published 2021-08-01

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

by Yuan Hou, Junfei Zhao, William Martin, Asha Kallianpur, Mina K. Chung, Lara Jehi, Nima Sharifi, Serpil Erzurum, Charis Eng, Feixiong Cheng
Published 2020-07-01

Rapid Mutation Scanning of Genes Associated with Familial Cancer Syndromes Using Denaturing High-Performance Liquid Chromatography

by Deborah J. Marsh, George Theodosopoulos, Viive Howell, Anne-Louise Richardson, Diana E. Benn, Anné L. Proos, Charis Eng, Bruce G. Robinson
Published 2001-01-01

Human breast microbiome correlates with prognostic features and immunological signatures in breast cancer

by Alice Tzeng, Naseer Sangwan, Margaret Jia, Chin-Chih Liu, Karen S. Keslar, Erinn Downs-Kelly, Robert L. Fairchild, Zahraa Al-Hilli, Stephen R. Grobmyer, Charis Eng
Published 2021-04-01