The Crosstalk between Cancer Stem Cells and Microenvironment Is Critical for Solid Tumor Progression: The Significant Contribution of Extracellular Vesicles

by Chiara Ciardiello, Alessandra Leone, Alfredo Budillon
Published 2018-01-01

Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches

by Alessandra Leone, Maria Serena Roca, Chiara Ciardiello, Susan Costantini, Alfredo Budillon
Published 2017-01-01

Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer

by Chiara Ciardiello, Lorenzo Cavallini, Cristiana Spinelli, Julie Yang, Mariana Reis-Sobreiro, Paola de Candia, Valentina Renè Minciacchi, Dolores Di Vizio
Published 2016-02-01

Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition

by Federica Iannelli, Maria Serena Roca, Rita Lombardi, Chiara Ciardiello, Laura Grumetti, Simona De Rienzo, Tania Moccia, Carlo Vitagliano, Angela Sorice, Susan Costantini, Maria Rita Milone, Biagio Pucci, Alessandra Leone, Elena Di Gennaro, Rita Mancini, Gennaro Ciliberto, Francesca Bruzzese, Alfredo Budillon
Published 2020-10-01

Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance

by Federica Iannelli, Andrea Ilaria Zotti, Maria Serena Roca, Laura Grumetti, Rita Lombardi, Tania Moccia, Carlo Vitagliano, Maria Rita Milone, Chiara Ciardiello, Francesca Bruzzese, Alessandra Leone, Ernesta Cavalcanti, Rossella De Cecio, Giuseppina Iachetta, Salvatore Valiante, Franco Ionna, Francesco Caponigro, Elena Di Gennaro, Alfredo Budillon
Published 2020-08-01

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

by Chiara Ciardiello, Alessandra Leone, Paola Lanuti, Maria S. Roca, Tania Moccia, Valentina R. Minciacchi, Michele Minopoli, Vincenzo Gigantino, Rossella De Cecio, Massimo Rippa, Lucia Petti, Francesca Capone, Carlo Vitagliano, Maria R. Milone, Biagio Pucci, Rita Lombardi, Federica Iannelli, Elena Di Gennaro, Francesca Bruzzese, Marco Marchisio, Maria V. Carriero, Dolores Di Vizio, Alfredo Budillon
Published 2019-07-01