Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

by Samer Haidar, Zouhair Bouaziz, Christelle Marminon, Tuomo Laitinen, Antti Poso, Marc Le Borgne, Joachim Jose
Published 2017-01-01

Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-<i>b</i>]indole Derivative, Discovered as CK2 Inhibitor

by Ehab El-Awaad, Robin Birus, Christelle Marminon, Zouhair Bouaziz, Laurens Ballentin, Dagmar Aichele, Marc Le Borgne, Joachim Jose
Published 2021-06-01

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′...

by Jennifer Hochscherf, Dirk Lindenblatt, Benedict Witulski, Robin Birus, Dagmar Aichele, Christelle Marminon, Zouhair Bouaziz, Marc Le Borgne, Joachim Jose, Karsten Niefind
Published 2017-12-01

Synthesis, Spectroscopic Characterization, and In Vitro Antibacterial Evaluation of Novel Functionalized Sulfamidocarbonyloxyphosphonates

by Abdeslem Bouzina, Khaoula Bechlem, Hajira Berredjem, Billel Belhani, Imène Becheker, Jacques Lebreton, Marc Le Borgne, Zouhair Bouaziz, Christelle Marminon, Malika Berredjem
Published 2018-07-01

Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7

by Abdelhamid Nacereddine, Andre Bollacke, Eszter Róka, Christelle Marminon, Zouhair Bouaziz, Ferenc Fenyvesi, Ildikó Katalin Bácskay, Joachim Jose, Florent Perret, Marc Le Borgne
Published 2018-01-01

QSAR Model of Indeno[1,2-<i>b</i>]indole Derivatives and Identification of <i>N</i>-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-<i>b</i>]furan-3-carboxamide as a Potent CK2...

by Samer Haidar, Christelle Marminon, Dagmar Aichele, Abdelhamid Nacereddine, Wael Zeinyeh, Abdeslem Bouzina, Malika Berredjem, Laurent Ettouati, Zouhair Bouaziz, Marc Le Borgne, Joachim Jose
Published 2019-12-01

Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

by Dirk Lindenblatt, Anna Nickelsen, Violetta M. Applegate, Jennifer Hochscherf, Benedict Witulski, Zouhair Bouaziz, Christelle Marminon, Maria Bretner, Marc Le Borgne, Joachim Jose, Karsten Niefind
Published 2019-03-01

Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds

by Sylwia Bloch, Bożena Nejman-Faleńczyk, Karolina Pierzynowska, Ewa Piotrowska, Alicja Węgrzyn, Christelle Marminon, Zouhair Bouaziz, Pascal Nebois, Joachim Jose, Marc Le Borgne, Luciano Saso, Grzegorz Węgrzyn
Published 2018-01-01

Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles

by Diogo Henrique Kita, Nathalie Guragossian, Ingrid Fatima Zattoni, Vivian Rotuno Moure, Fabiane Gomes de Moraes Rego, Sabrina Lusvarghi, Thomas Moulenat, Billel Belhani, Geraldo Picheth, Sofiane Bouacida, Zouhair Bouaziz, Christelle Marminon, Malika Berredjem, Joachim Jose, Marcos Brown Gonçalves, Suresh V. Ambudkar, Glaucio Valdameri, Marc Le Borgne
Published 2021-01-01