Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity

by Sabrina Rueschenbaum, Sabrina Rueschenbaum, Chengcong Cai, Matthias Schmidt, Katharina Schwarzkopf, Ulf Dittmer, Stefan Zeuzem, Christoph Welsch, Christian M. Lange, Christian M. Lange
Published 2021-01-01

Dysregulated Adaptive Immunity Is an Early Event in Liver Cirrhosis Preceding Acute-on-Chronic Liver Failure

by Sabrina Rueschenbaum, Sabrina Rueschenbaum, Sandra Ciesek, Alexander Queck, Marek Widera, Katharina Schwarzkopf, Bernhard Brüne, Christoph Welsch, Heiner Wedemeyer, Stefan Zeuzem, Andreas Weigert, Christian M. Lange, Christian M. Lange
Published 2021-01-01

Standard coagulation tests are superior to thromboelastometry in predicting outcome of patients with liver cirrhosis.

by Jassin Rashidi-Alavijeh, Ayse S Ceylan, Heiner Wedemeyer, Martin Kleefisch, Katharina Willuweit, Christian M Lange
Published 2020-01-01

Glycogen Synthase Kinase 3β Enhances Hepatitis C Virus Replication by Supporting miR-122

by Maged Saleh, Sabrina Rüschenbaum, Christoph Welsch, Stefan Zeuzem, Darius Moradpour, Jérôme Gouttenoire, Christian M. Lange
Published 2018-11-01

Hypopituitarism in Wilson’s disease resolved after copper-chelating therapy

by Nina Dauth, Victoria T Mücke, Marcus M Mücke, Christian M Lange, Martin Welker, Stefan Zeuzem, Klaus Badenhoop
Published 2021-01-01

Differential Kinetics of Coagulation Factors and Natural Anticoagulants in Patients with Liver Cirrhosis: Potential Clinical Implications.

by Michael Tischendorf, Wolfgang Miesbach, Umer Chattah, Zenab Chattah, Sebastian Maier, Christoph Welsch, Stefan Zeuzem, Christian M Lange
Published 2016-01-01

Ongoing liver inflammation in patients with chronic hepatitis C and sustained virological response.

by Christoph Welsch, Mira Efinger, Michael von Wagner, Eva Herrmann, Stefan Zeuzem, Tania M Welzel, Christian M Lange
Published 2017-01-01

Enzymatic liver function measured by LiMAx is superior to current standard methods in predicting transplant-free survival after TIPS implantation

by Jassin Rashidi-Alavijeh, Alisan Kahraman, Guido Gerken, Jens M. Theysohn, Katharina Willuweit, Dieter P. Hoyer, Christian M. Lange, Matthias Buechter
Published 2021-07-01

Stool and sputum microbiome during quinolone prophylaxis of spontaneous bacterial peritonitis: an exploratory study

by Marcus M. Mücke, Sabrina Rüschenbaum, Amelie Mayer, Victoria T. Mücke, Katharina M. Schwarzkopf, Stefan Zeuzem, Jan Kehrmann, René Scholtysik, Christian M. Lange
Published 2020-10-01

The role of Enterococcus spp. and multidrug-resistant bacteria causing pyogenic liver abscesses

by Marcus M. Mücke, Johanna Kessel, Victoria T. Mücke, Katharina Schwarzkopf, Michael Hogardt, Christoph Stephan, Stefan Zeuzem, Volkhard A. J. Kempf, Christian M. Lange
Published 2017-06-01

Vitamin D deficiency is associated with hepatic decompensation and inflammation in patients with liver cirrhosis: A prospective cohort study.

by Alica Kubesch, Leonie Quenstedt, Maged Saleh, Sabrina Rüschenbaum, Katharina Schwarzkopf, Yolanda Martinez, Christoph Welsch, Stefan Zeuzem, Tania M Welzel, Christian M Lange
Published 2018-01-01

Serum Sphingosine‐1‐Phosphate Is Decreased in Patients With Acute‐on‐Chronic Liver Failure and Predicts Early Mortality

by Victoria T. Mücke, Katharina Maria Schwarzkopf, Dominique Thomas, Marcus M. Mücke, Sabrina Rüschenbaum, Jonel Trebicka, Josef Pfeilschifter, Stefan Zeuzem, Christian M. Lange, Georgios Grammatikos
Published 2020-10-01

Use of Antiplatelet Agents Is Inversely Associated With Liver Fibrosis in Patients With Cardiovascular Disease

by Katharina Schwarzkopf, Joerg Bojunga, Sabrina Rüschenbaum, Yolanda Martinez, Marcus M. Mücke, Florian Seeger, Fabian Schoelzel, Stefan Zeuzem, Mireen Friedrich‐Rust, Christian M. Lange
Published 2018-12-01

Humoral Response to SARS-Cov-2 Vaccination in Liver Transplant Recipients–A Single-Center Experience

by Jassin Rashidi-Alavijeh, Alexandra Frey, Moritz Passenberg, Johannes Korth, Jaqueline Zmudzinski, Olympia E. Anastasiou, Fuat H. Saner, Michael Jahn, Christian M. Lange, Katharina Willuweit
Published 2021-07-01

Macrophage-Derived Extracellular Vesicles Induce Long-Lasting Immunity Against Hepatitis C Virus Which Is Blunted by Polyunsaturated Fatty Acids

by Chengcong Cai, Benjamin Koch, Kenichi Morikawa, Goki Suda, Naoya Sakamoto, Sabrina Rueschenbaum, Sami Akhras, Julia Dietz, Eberhard Hildt, Stefan Zeuzem, Christoph Welsch, Christian M. Lange
Published 2018-04-01

GALAD Score Detects Early-Stage Hepatocellular Carcinoma in a European Cohort of Chronic Hepatitis B and C Patients

by Clemens Schotten, Bastian Ostertag, Jan-Peter Sowa, Paul Manka, Lars P. Bechmann, Gudrun Hilgard, Claudio Marquardt, Marc Wichert, Hidenori Toyoda, Christian M. Lange, Ali Canbay, Philip Johnson, Heiner Wedemeyer, Jan Best
Published 2021-07-01

Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis

by Alexander Queck, Annika F. Fink, Evelyn Sirait-Fischer, Sabrina Rüschenbaum, Dominique Thomas, Ryan G. Snodgrass, Gerd Geisslinger, Gerd Geisslinger, Hideo A. Baba, Jonel Trebicka, Jonel Trebicka, Jonel Trebicka, Jonel Trebicka, Stefan Zeuzem, Andreas Weigert, Christian M. Lange, Bernhard Brüne, Bernhard Brüne
Published 2020-07-01

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C.

by Christian M Lange, Stephanie Bibert, Zoltan Kutalik, Philippe Burgisser, Andreas Cerny, Jean-Francois Dufour, Andreas Geier, Tilman J Gerlach, Markus H Heim, Raffaele Malinverni, Francesco Negro, Stephan Regenass, Klaus Badenhoop, Jörg Bojunga, Christoph Sarrazin, Stefan Zeuzem, Tobias Müller, Thomas Berg, Pierre-Yves Bochud, Darius Moradpour, Swiss Hepatitis C Cohort Study Group
Published 2012-01-01

Cabozantinib in Advanced Hepatocellular Carcinoma: Efficacy and Safety Data from an International Multicenter Real-Life Cohort

by Fabian Finkelmeier, Bernhard Scheiner, Catherine Leyh, Jan Best, Thorben Wilhelm Fründt, Carolin Czauderna, Alica Beutel, Dominik Bettinger, Johannes Weiß, Tobias Meischl, Fabian Kütting, Dirk-Thomas Waldschmidt, Pompilia Radu, Michael Schultheiß, Kai-Henrik Peiffer, Thomas J. Ettrich, Arndt Weinmann, Henning Wege, Marino Venerito, Jean-Francois Dufour, Christian M. Lange, Matthias Pinter, Oliver Waidmann
Published 2021-06-01

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development.

by Christian M Lange, Daiki Miki, Hidenori Ochi, Hans-Dieter Nischalke, Jörg Bojunga, Stéphanie Bibert, Kenichi Morikawa, Jérôme Gouttenoire, Andreas Cerny, Jean-François Dufour, Meri Gorgievski-Hrisoho, Markus H Heim, Raffaele Malinverni, Beat Müllhaupt, Francesco Negro, David Semela, Zoltan Kutalik, Tobias Müller, Ulrich Spengler, Thomas Berg, Kazuaki Chayama, Darius Moradpour, Pierre-Yves Bochud, Hiroshima Liver Study Group, Swiss Hepatitis C Cohort Study Group
Published 2013-01-01