The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders

by Inês S. Amorim, Gilliard Lach, Christos G. Gkogkas, Christos G. Gkogkas
Published 2018-11-01

The translational landscape of ground state pluripotency

by Yaser Atlasi, Seyed Mehdi Jafarnejad, Christos G. Gkogkas, Michiel Vermeulen, Nahum Sonenberg, Hendrik G. Stunnenberg
Published 2020-04-01

Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain

by Sonali Uttam, Calvin Wong, Inês S. Amorim, Seyed Mehdi Jafarnejad, Shannon N. Tansley, Jieyi Yang, Masha Prager-Khoutorsky, Jeffrey S. Mogil, Christos G. Gkogkas, Arkady Khoutorsky
Published 2018-08-01

Induction of an Alternative mRNA 5′ Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection

by Huy-Dung Hoang, Tyson E. Graber, Jian-Jun Jia, Nasana Vaidya, Victoria H. Gilchrist, Xiao Xiang, Wencheng Li, Kyle N. Cowan, Christos G. Gkogkas, Maritza Jaramillo, Seyed Mehdi Jafarnejad, Tommy Alain
Published 2019-12-01

Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity

by Stella Kouloulia, Erik I. Hallin, Konstanze Simbriger, Inês S. Amorim, Gilliard Lach, Theoklitos Amvrosiadis, Kleanthi Chalkiadaki, Agniete Kampaite, Vinh Tai Truong, Mehdi Hooshmandi, Seyed Mehdi Jafarnejad, Paul Skehel, Petri Kursula, Arkady Khoutorsky, Christos G. Gkogkas
Published 2019-12-01

Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1

by Patricia Soriano Roque, Mehdi Hooshmandi, Laura Neagu-Lund, Shelly Yin, Noosha Yousefpour, Hiroaki Sato, Tamaki Sato, Yosuke Nakadate, Akiko Kawakami, Soroush Tahmasebi, Alfredo Ribeiro-da-Silva, Christos G. Gkogkas, Masha Prager-Khoutorsky, Thomas Schricker, Linda Wykes, Arkady Khoutorsky
Published 2021-07-01

Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

by Christos G. Gkogkas, Arkady Khoutorsky, Ruifeng Cao, Seyed Mehdi Jafarnejad, Masha Prager-Khoutorsky, Nikolaos Giannakas, Archontia Kaminari, Apostolia Fragkouli, Karim Nader, Theodore J. Price, Bruce W. Konicek, Jeremy R. Graff, Athina K. Tzinia, Jean-Claude Lacaille, Nahum Sonenberg
Published 2014-12-01

Translational control of nociception via 4E-binding protein 1

by Arkady Khoutorsky, Robert P Bonin, Robert E Sorge, Christos G Gkogkas, Sophie Anne Pawlowski, Seyed Mehdi Jafarnejad, Mark H Pitcher, Tommy Alain, Jimena Perez-Sanchez, Eric W Salter, Loren Martin, Alfredo Ribeiro-da-Silva, Yves De Koninck, Fernando Cervero, Jeffrey S Mogil, Nahum Sonenberg
Published 2015-12-01

Translational control of ERK signaling through miRNA/4EHP-directed silencing

by Seyed Mehdi Jafarnejad, Clément Chapat, Edna Matta-Camacho, Idit Anna Gelbart, Geoffrey G Hesketh, Meztli Arguello, Aitor Garzia, Sung-Hoon Kim, Jan Attig, Maayan Shapiro, Masahiro Morita, Arkady Khoutorsky, Tommy Alain, Christos, G Gkogkas, Noam Stern-Ginossar, Thomas Tuschl, Anne-Claude Gingras, Thomas F Duchaine, Nahum Sonenberg
Published 2018-02-01