Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis

by Margherita Passariello, Cinzia Vetrei, Felice Amato, Claudia De Lorenzo
Published 2021-08-01

Novel Human Bispecific Aptamer–Antibody Conjugates for Efficient Cancer Cell Killing

by Margherita Passariello, Simona Camorani, Cinzia Vetrei, Laura Cerchia, Claudia De Lorenzo
Published 2019-08-01

Ipilimumab and Its Derived EGFR Aptamer-Based Conjugate Induce Efficient NK Cell Activation against Cancer Cells

by Margherita Passariello, Simona Camorani, Cinzia Vetrei, Stefania Ricci, Laura Cerchia, Claudia De Lorenzo
Published 2020-02-01

Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

by Cinzia Vetrei, Margherita Passariello, Guendalina Froechlich, Rosa Rapuano Lembo, Nicola Zambrano, Claudia De Lorenzo
Published 2021-06-01

Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production

by Gennaro Riccio, Salvatore Antonucci, Carmela Coppola, Chiara D'Avino, Chiara D'Avino, Giovanna Piscopo, Danilo Fiore, Carlo Maurea, Michele Russo, Domenica Rea, Claudio Arra, Gerolama Condorelli, Fabio Di Lisa, Carlo G. Tocchetti, Claudia De Lorenzo, Claudia De Lorenzo, Nicola Maurea
Published 2018-02-01

Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling

by Margherita Passariello, Anna Morena D’Alise, Annachiara Esposito, Cinzia Vetrei, Guendalina Froechlich, Elisa Scarselli, Alfredo Nicosia, Claudia De Lorenzo
Published 2019-09-01

One-Step Recovery of scFv Clones from High-Throughput Sequencing-Based Screening of Phage Display Libraries Challenged to Cells Expressing Native Claudin-1

by Emanuele Sasso, Rolando Paciello, Francesco D’Auria, Gennaro Riccio, Guendalina Froechlich, Riccardo Cortese, Alfredo Nicosia, Claudia De Lorenzo, Nicola Zambrano
Published 2015-01-01

Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models

by Vincenzo Quagliariello, Margherita Passariello, Domenica Rea, Antonio Barbieri, Martina Iovine, Annamaria Bonelli, Antonietta Caronna, Gerardo Botti, Claudia De Lorenzo, Nicola Maurea
Published 2020-10-01

Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells

by Margherita Passariello, Cinzia Vetrei, Emanuele Sasso, Guendalina Froechlich, Chiara Gentile, Anna Morena D’Alise, Nicola Zambrano, Elisa Scarselli, Alfredo Nicosia, Claudia De Lorenzo
Published 2020-08-01

Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2

by Margherita Passariello, Chiara Gentile, Veronica Ferrucci, Emanuele Sasso, Cinzia Vetrei, Giovanna Fusco, Maurizio Viscardi, Sergio Brandi, Pellegrino Cerino, Nicola Zambrano, Massimo Zollo, Claudia De Lorenzo
Published 2021-05-01

Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer

by Simona Camorani, Margherita Passariello, Lisa Agnello, Silvia Esposito, Francesca Collina, Monica Cantile, Maurizio Di Bonito, Ilya V. Ulasov, Monica Fedele, Antonella Zannetti, Claudia De Lorenzo, Laura Cerchia
Published 2020-09-01

Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries

by Biancamaria Cembrola, Valentino Ruzza, Fulvia Troise, Maria Luisa Esposito, Emanuele Sasso, Valeria Cafaro, Margherita Passariello, Feliciano Visconte, Maddalena Raia, Luigi Del Vecchio, Anna Morena D’Alise, Riccardo Cortese, Elisa Scarselli, Nicola Zambrano, Claudia De Lorenzo, Alfredo Nicosia
Published 2019-01-01