Competitive Activity-Based Protein Profiling Identifies Aza-β-Lactams as a Versatile Chemotype for Serine Hydrolase Inhibition

by Zuhl, Andrea M., Mohr, Justin T., Bachovchin, Daniel A., Niessen, Sherry, Hsu, Ku-Lung, Berlin, Jacob M., Dochnahl, Maximilian, Fu, Gregory C., Cravatt, Benjamin F., Lopez-Alberca, Maria P.
Published 2013

Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors

by Mohr, Justin T., Speers, Anna E., Wan, Chu, Spicer, Timothy P., Fernandez-Vega, Virneliz, Chase, Peter, Hodder, Peter S., Schürer, Stephan C., Nomura, Daniel K., Rosen, Hugh, Cravatt, Benjamin F., Bachovchin, Daniel A., Berlin, Jacob M., Fu, Gregory C.
Published 2011

Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases

by Guo, Chun-Jun, Chang, Fang-Yuan, Wyche, Thomas P., Backus, Keriann M., Acker, Timothy M., Funabashi, Masanori, Taketani, Mao, Donia, Mohamed S., Nayfach, Stephen, Pollard, Katherine S., Craik, Charles S., Cravatt, Benjamin F., Clardy, Jon, Voigt, Christopher A., Fischbach, Michael A.
Published 2018

Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium

by Pentinmikko, Nalle, Iqbal, Sharif, Mana, Miyeko, Andersson, Simon, Cognetta, Armand B., Suciu, Radu M., Roper, Jatin, Luopajärvi, Kalle, Markelin, Eino, Gopalakrishnan, Swetha, Smolander, Olli-Pekka, Naranjo, Santiago, Saarinen, Tuure, Juuti, Anne, Pietiläinen, Kirsi, Auvinen, Petri, Ristimäki, Ari, Gupta, Nitin, Tammela, Tuomas, Jacks, Tyler E, Sabatini, David, Cravatt, Benjamin F., Yilmaz, Ömer H., Katajisto, Pekka
Published 2020

How many human proteoforms are there?

by Aebersold, Ruedi, Agar, Jeffrey N, Amster, I Jonathan, Baker, Mark S, Bertozzi, Carolyn R, Boja, Emily S, Costello, Catherine E, Cravatt, Benjamin F, Fenselau, Catherine, Garcia, Benjamin A, Ge, Ying, Gunawardena, Jeremy, Hendrickson, Ronald C, Hergenrother, Paul J, Huber, Christian G, Ivanov, Alexander R, Jensen, Ole N, Jewett, Michael C, Kelleher, Neil L, Krogan, Nevan J, Larsen, Martin R, Loo, Joseph A, Ogorzalek Loo, Rachel R, Lundberg, Emma, MacCoss, Michael J, Mallick, Parag, Mootha, Vamsi K, Mrksich, Milan, Muir, Tom W, Patrie, Steven M, Pesavento, James J, Pitteri, Sharon J, Rodriguez, Henry, Saghatelian, Alan, Sandoval, Wendy, Schlüter, Hartmut, Sechi, Salvatore, Slavoff, Sarah A, Smith, Lloyd M, Snyder, Michael P, Thomas, Paul M, Uhlén, Mathias, Van Eyk, Jennifer E, Vidal, Marc, Walt, David R, White, Forest M, Williams, Evan R, Wohlschlager, Therese, Wysocki, Vicki H, Yates, Nathan A, Young, Nicolas L, Zhang, Bing, Kiessling, Laura L
Published 2019