Role of pharmacogenetics for the improvement of cancer treatment

by Vita Dolžan, Petra Bohanec-Grabar, Cristina Rodriguez-Antona
Published 2007-12-01

Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene.

by Miljana Tanic, Kira Yanowsky, Cristina Rodriguez-Antona, Raquel Andrés, Iván Márquez-Rodas, Ana Osorio, Javier Benitez, Beatriz Martinez-Delgado
Published 2012-01-01

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation

by Marta Espinosa, Juan Maria Roldán-Romero, Ignacio Duran, Enrique de Álava, María Apellaniz-Ruiz, Alberto Cascón, Carmen Garrigos, Mercedes Robledo, Cristina Rodriguez-Antona
Published 2018-05-01

Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer.

by Tomas Pascual, María Apellániz-Ruiz, Cristina Pernaut, Cecilia Cueto-Felgueroso, Pablo Villalba, Carlos Álvarez, Luis Manso, Lucia Inglada-Pérez, Mercedes Robledo, Cristina Rodríguez-Antona, Eva Ciruelos
Published 2017-01-01

Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates

by Miriam Saiz-Rodríguez, Susana Almenara, Marcos Navares-Gómez, Dolores Ochoa, Manuel Román, Pablo Zubiaur, Dora Koller, María Santos, Gina Mejía, Alberto M. Borobia, Cristina Rodríguez-Antona, Francisco Abad-Santos
Published 2020-04-01

Overexpression of miR‐483‐5p is confined to metastases and linked to high circulating levels in patients with metastatic pheochromocytoma/paraganglioma

by Luis Jaime Castro‐Vega, Bruna Calsina, Nelly Burnichon, Tom Drossart, Ángel M Martínez‐Montes, Virginie Verkarre, Laurence Amar, Jérôme Bertherat, Cristina Rodríguez‐Antona, Judith Favier, Mercedes Robledo, Anne‐Paule Gimenez‐Roqueplo
Published 2020-12-01

MicroRNAs Targeting HIF-2α, VEGFR1 and/or VEGFR2 as Potential Predictive Biomarkers for VEGFR Tyrosine Kinase and HIF-2α Inhibitors in Metastatic Clear-Cell Renal Cell Carcinoma

by Lisa Kinget, Eduard Roussel, Annelies Verbiest, Maarten Albersen, Cristina Rodríguez-Antona, Osvaldo Graña-Castro, Lucía Inglada-Pérez, Jessica Zucman-Rossi, Gabrielle Couchy, Sylvie Job, Aurélien de Reyniès, Annouschka Laenen, Marcella Baldewijns, Benoit Beuselinck
Published 2021-06-01

MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets.

by Annelies Verbiest, Vincent Van Hoef, Cristina Rodriguez-Antona, Jesús García-Donas, Osvaldo Graña-Castro, Maarten Albersen, Marcella Baldewijns, Annouschka Laenen, Eduard Roussel, Patrick Schöffski, Agnieszka Wozniak, Stefano Caruso, Gabrielle Couchy, Jessica Zucman-Rossi, Benoit Beuselinck
Published 2020-01-01

A Novel Approach for the Identification of Pharmacogenetic Variants in <i>MT-RNR1</i> through Next-Generation Sequencing Off-Target Data

by Javier Lanillos, María Santos, Marta Carcajona, Juan María Roldan-Romero, Angel M. Martinez, Bruna Calsina, María Monteagudo, Luis Javier Leandro-García, Cristina Montero-Conde, Alberto Cascón, Paolo Maietta, Sara Alvarez, Mercedes Robledo, Cristina Rodriguez-Antona
Published 2020-07-01

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

by Lisa Kinget, Eduard Roussel, Diether Lambrechts, Bram Boeckx, Loïc Vanginderhuysen, Maarten Albersen, Cristina Rodríguez-Antona, Osvaldo Graña-Castro, Lucía Inglada-Pérez, Annelies Verbiest, Jessica Zucman-Rossi, Gabrielle Couchy, Stefano Caruso, Annouschka Laenen, Marcella Baldewijns, Benoit Beuselinck
Published 2021-03-01

MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets

by Annelies Verbiest, Vincent Van Hoef, Cristina Rodriguez-Antona, Jesús García-Donas, Osvaldo Graña-Castro, Maarten Albersen, Marcella Baldewijns, Annouschka Laenen, Eduard Roussel, Patrick Schöffski, Agnieszka Wozniak, Stefano Caruso, Gabrielle Couchy, Jessica Zucman-Rossi, Benoit Beuselinck, Olorunseun Ogunwobi
Published 2020-01-01

Circulating Levels of the Interferon-γ-Regulated Chemokines CXCL10/CXCL11, IL-6 and HGF Predict Outcome in Metastatic Renal Cell Carcinoma Patients Treated with Antiangiogenic Ther...

by Emilio Esteban, Francisco Exposito, Guillermo Crespo, Julio Lambea, Alvaro Pinto, Javier Puente, Jose A. Arranz, Miriam Redrado, Cristina Rodriguez-Antona, Carlos de Andrea, Marta Lopez-Brea, Esther Redin, Angel Rodriguez, Diego Serrano, Jorge Garcia, Enrique Grande, Daniel Castellano, Alfonso Calvo
Published 2021-06-01

Novel <i>DNMT3A</i> Germline Variant in a Patient with Multiple Paragangliomas and Papillary Thyroid Carcinoma

by Sara Mellid, Javier Coloma, Bruna Calsina, María Monteagudo, Juan M. Roldán-Romero, María Santos, Luis J. Leandro-García, Javier Lanillos, Ángel M. Martínez-Montes, Cristina Rodríguez-Antona, Cristina Montero-Conde, Joaquín Martínez-López, Rosa Ayala, Xavier Matias-Guiu, Mercedes Robledo, Alberto Cascón
Published 2020-11-01

Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma.

by Celia Prior, Jose Luis Perez-Gracia, Jesus Garcia-Donas, Cristina Rodriguez-Antona, Elizabeth Guruceaga, Emilio Esteban, Cristina Suarez, Daniel Castellano, Aránzazu González del Alba, Maria Dolores Lozano, Joan Carles, Miguel Angel Climent, Jose Angel Arranz, Enrique Gallardo, Javier Puente, Joaquim Bellmunt, Alfonso Gurpide, Jose Maria Lopez-Picazo, Alvaro Gonzalez Hernandez, Begoña Mellado, Esther Martínez, Fernando Moreno, Albert Font, Alfonso Calvo
Published 2014-01-01

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

by Iñigo Landa, Sergio Ruiz-Llorente, Cristina Montero-Conde, Lucía Inglada-Pérez, Lucía Inglada-Pérez, Francesca Schiavi, Susanna Leskelä, Guillermo Pita, Roger Milne, Javier Maravall, Ignacio Ramos, Víctor Andía, Paloma Rodríguez-Poyo, Antonino Jara-Albarrán, Amparo Meoro, Cristina del Peso, Luis Arribas, Pedro Iglesias, Javier Caballero, Joaquín Serrano, Antonio Picó, Francisco Pomares, Gabriel Giménez, Pedro López-Mondéjar, Roberto Castello, Isabella Merante-Boschin, Maria-Rosa Pelizzo, Didac Mauricio, Giuseppe Opocher, Cristina Rodríguez-Antona, Anna González-Neira, Xavier Matías-Guiu, Pilar Santisteban, Mercedes Robledo
Published 2009-09-01