Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration

by Parameswaran G. Sreekumar, Deborah A. Ferrington, Ram Kannan
Published 2021-04-01

Molecular Mechanisms Underlying Age-Related Ocular Diseases

by Marialaura Amadio, Kai Kaarniranta, Heping Xu, Adrian Smedowski, Deborah A. Ferrington
Published 2018-01-01

Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome.

by Haiming M Liu, Deborah A Ferrington, Cory W Baumann, LaDora V Thompson
Published 2016-01-01

Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells.

by Md Razaul Karim, Cody R Fisher, Rebecca J Kapphahn, Jorge R Polanco, Deborah A Ferrington
Published 2020-01-01

Improving retinal mitochondrial function as a treatment for age-related macular degeneration

by Mara C. Ebeling, Jorge R. Polanco, Jun Qu, Chengjian Tu, Sandra R. Montezuma, Deborah A. Ferrington
Published 2020-07-01

Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy

by Maria Hytti, Eveliina Korhonen, Juha M. T. Hyttinen, Heidi Roehrich, Kai Kaarniranta, Deborah A. Ferrington, Anu Kauppinen
Published 2019-01-01

Immunoproteasome deficiency modifies the alternative pathway of NFκB signaling.

by Marcela Maldonado, Rebecca J Kapphahn, Marcia R Terluk, Neal D Heuss, Ching Yuan, Dale S Gregerson, Deborah A Ferrington
Published 2013-01-01

Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration

by Mara C. Ebeling, Zhaohui Geng, Rebecca J. Kapphahn, Heidi Roehrich, Sandra R. Montezuma, James R. Dutton, Deborah A. Ferrington
Published 2021-04-01

N-Acetyl-L-cysteine Protects Human Retinal Pigment Epithelial Cells from Oxidative Damage: Implications for Age-Related Macular Degeneration

by Marcia R. Terluk, Mara C. Ebeling, Cody R. Fisher, Rebecca J. Kapphahn, Ching Yuan, Reena V. Kartha, Sandra R. Montezuma, Deborah A. Ferrington
Published 2019-01-01

Immunoproteasome deficiency protects in the retina after optic nerve crush.

by Nathan J Schuld, Stacy A Hussong, Rebecca J Kapphahn, Ute Lehmann, Heidi Roehrich, Abrar A Rageh, Neal D Heuss, Wendy Bratten, Dale S Gregerson, Deborah A Ferrington
Published 2015-01-01

Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration.

by Zhouhui Geng, Patrick J Walsh, Vincent Truong, Caitlin Hill, Mara Ebeling, Rebecca J Kapphahn, Sandra R Montezuma, Ching Yuan, Heidi Roehrich, Deborah A Ferrington, James R Dutton
Published 2017-01-01

Corneal wound healing is compromised by immunoproteasome deficiency.

by Deborah A Ferrington, Heidi Roehrich, Angela A Chang, Craig W Huang, Marcela Maldonado, Wendy Bratten, Abrar A Rageh, Neal D Heuss, Dale S Gregerson, Elizabeth F Nelson, Ching Yuan
Published 2013-01-01

Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration

by Deborah A. Ferrington, Mara C. Ebeling, Rebecca J. Kapphahn, Marcia R. Terluk, Cody R. Fisher, Jorge R. Polanco, Heidi Roehrich, Michaela M. Leary, Zhaohui Geng, James R. Dutton, Sandra R. Montezuma
Published 2017-10-01

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

by Szabolcs Felszeghy, Johanna Viiri, Jussi J. Paterno, Juha M.T. Hyttinen, Ali Koskela, Mei Chen, Henri Leinonen, Heikki Tanila, Niko Kivinen, Arto Koistinen, Elisa Toropainen, Marialaura Amadio, Adrian Smedowski, Mika Reinisalo, Mateusz Winiarczyk, Jerzy Mackiewicz, Maija Mutikainen, Anna-Kaisa Ruotsalainen, Mikko Kettunen, Kimmo Jokivarsi, Debasish Sinha, Kati Kinnunen, Goran Petrovski, Janusz Blasiak, Geir Bjørkøy, Ari Koskelainen, Heli Skottman, Arto Urtti, Antero Salminen, Ram Kannan, Deborah A. Ferrington, Heping Xu, Anna-Liisa Levonen, Pasi Tavi, Anu Kauppinen, Kai Kaarniranta
Published 2019-01-01