A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors

by Rajaa El Meskini, Anthony J. Iacovelli, Alan Kulaga, Michelle Gumprecht, Philip L. Martin, Maureen Baran, Deborah B. Householder, Terry Van Dyke, Zoë Weaver Ohler
Published 2015-01-01

Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.

by Ludmila Szabova, Sujata Bupp, Muhaymin Kamal, Deborah B Householder, Lidia Hernandez, Jerome J Schlomer, Maureen L Baran, Ming Yi, Robert M Stephens, Christina M Annunziata, Philip L Martin, Terry A Van Dyke, Zoe Weaver Ohler, Simone Difilippantonio
Published 2014-01-01