Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix.

by Jessica M Gluck, Anthony W Herren, Sergey Yechikov, Hillary K J Kao, Ambereen Khan, Brett S Phinney, Nipavan Chiamvimonvat, James W Chan, Deborah K Lieu
Published 2017-01-01

Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes crucial for mat...

by Ellen Poon, Bin Yan, Shaohong Zhang, Stephanie Rushing, Wendy Keung, Lihuan Ren, Deborah K Lieu, Lin Geng, Chi-Wing Kong, Jiaxian Wang, Hau San Wong, Kenneth R Boheler, Ronald A Li
Published 2013-01-01

NODAL inhibition promotes differentiation of pacemaker-like cardiomyocytes from human induced pluripotent stem cells

by Sergey Yechikov, Hillary K.J. Kao, Che-Wei Chang, Dalyir Pretto, Xiao-Dong Zhang, Yao-Hui Sun, Regan Smithers, Padmini Sirish, Jan A. Nolta, James W. Chan, Nipavan Chiamvimonvat, Deborah K. Lieu
Published 2020-12-01

Correlation between frataxin expression and contractility revealed by in vitro Friedreich’s ataxia cardiac tissue models engineered from human pluripotent stem cells

by Andy On-Tik Wong, Gabriel Wong, Michael Shen, Maggie Zi-Ying Chow, Wan Wai Tse, Bimal Gurung, Suet Yee Mak, Deborah K. Lieu, Kevin D. Costa, Camie W. Chan, Alain Martelli, Joseph F. Nabhan, Ronald A. Li
Published 2019-07-01

Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes.

by Ji-Dong Fu, Stephanie N Rushing, Deborah K Lieu, Camie W Chan, Chi-Wing Kong, Lin Geng, Kitchener D Wilson, Nipavan Chiamvimonvat, Kenneth R Boheler, Joseph C Wu, Gordon Keller, Roger J Hajjar, Ronald A Li
Published 2011-01-01