Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein

by Andre Leitao, Akshay Bhumkar, Dominic J. B. Hunter, Yann Gambin, Emma Sierecki
Published 2018-01-01

A Split-Luciferase Reporter Recognizing GFP and mCherry Tags to Facilitate Studies of Protein–Protein Interactions

by Mehdi Moustaqil, Akshay Bhumkar, Laura Gonzalez, Lisa Raoul, Dominic J. B. Hunter, Pascal Carrive, Emma Sierecki, Yann Gambin
Published 2017-12-01

Single-molecule detection on a portable 3D-printed microscope

by James W. P. Brown, Arnaud Bauer, Mark E Polinkovsky, Akshay Bhumkar, Dominic J. B. Hunter, Katharina Gaus, Emma Sierecki, Yann Gambin
Published 2019-12-01

Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein

by André D. G. Leitão, Paulina Rudolffi-Soto, Alexandre Chappard, Akshay Bhumkar, Derrick Lau, Dominic J. B. Hunter, Yann Gambin, Emma Sierecki
Published 2021-09-01

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

by Ailís O’Carroll, Brieuc Chauvin, James W. P. Brown, Ava Meagher, Joanne Coyle, Jurgen Schill, Akshay Bhumkhar, Dominic J. B. Hunter, Thomas Ve, Bostjan Kobe, Emma Sierecki, Yann Gambin
Published 2018-12-01

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

by Max T. B. Clabbers, Susannah Holmes, Timothy W. Muusse, Parimala R. Vajjhala, Sara J. Thygesen, Alpeshkumar K. Malde, Dominic J. B. Hunter, Tristan I. Croll, Leonie Flueckiger, Jeffrey D. Nanson, Md. Habibur Rahaman, Andrew Aquila, Mark S. Hunter, Mengning Liang, Chun Hong Yoon, Jingjing Zhao, Nadia A. Zatsepin, Brian Abbey, Emma Sierecki, Yann Gambin, Katryn J. Stacey, Connie Darmanin, Bostjan Kobe, Hongyi Xu, Thomas Ve
Published 2021-05-01