The effect of hyperglycaemia on in vitro cytokine production and macrophage infection with Mycobacterium tuberculosis.

by Ekta Lachmandas, Frank Vrieling, Louis G Wilson, Simone A Joosten, Mihai G Netea, Tom H Ottenhoff, Reinout van Crevel
Published 2015-01-01

Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids

by Ekta Lachmandas, Corina N. A. M. van den Heuvel, Michelle S. M. A. Damen, Maartje C. P. Cleophas, Mihai G. Netea, Reinout van Crevel
Published 2016-01-01

Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis.

by Jorge Domínguez-Andrés, Rob J W Arts, Rob Ter Horst, Mark S Gresnigt, Sanne P Smeekens, Jacqueline M Ratter, Ekta Lachmandas, Lily Boutens, Frank L van de Veerdonk, Leo A B Joosten, Richard A Notebaart, Carlos Ardavín, Mihai G Netea
Published 2017-09-01

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

by Julia Böhme, Nuria Martinez, Shamin Li, Andrea Lee, Mardiana Marzuki, Anteneh Mehari Tizazu, David Ackart, Jessica Haugen Frenkel, Alexandra Todd, Ekta Lachmandas, Josephine Lum, Foo Shihui, Tze Pin Ng, Bernett Lee, Anis Larbi, Mihai G. Netea, Randall Basaraba, Reinout van Crevel, Evan Newell, Hardy Kornfeld, Amit Singhal
Published 2020-10-01