A30P α-synuclein impairs dopaminergic fiber regeneration and interacts with L-DOPA replacement in MPTP-treated mice

by Éva M. Szegő, Ellen Gerhardt, Pawel Kermer, Jörg B. Schulz
Published 2012-01-01

Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.

by Ellen Gerhardt, Simone Gräber, Eva M Szego, Nicoleta Moisoi, L Miguel Martins, Tiago F Outeiro, Pawel Kermer
Published 2011-01-01

Potential Synergistic Protection of Retinal Ganglion Cells from Axotomy-Induced Apoptosis by Adenoviral Administration of Glial Cell Line-Derived Neurotrophic Factor and X-Chromoso...

by Guido Straten, Christian Schmeer, Alexandra Kretz, Ellen Gerhardt, Sebastian Kügler, Jörg B. Schulz, Claude Gravel, Mathias Bähr, Stefan Isenmann
Published 2002-10-01

The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.

by Erin K Butler, Aaron Voigt, A Kathrin Lutz, Jane P Toegel, Ellen Gerhardt, Peter Karsten, Björn Falkenburger, Andrea Reinartz, Konstanze F Winklhofer, Jörg B Schulz
Published 2012-02-01

Membrane binding, internalization, and sorting of alpha-synuclein in the cell

by Caterina Masaracchia, Marilena Hnida, Ellen Gerhardt, Tomás Lopes da Fonseca, Anna Villar-Pique, Tiago Branco, Markus A. Stahlberg, Camin Dean, Claudio O. Fernández, Ira Milosevic, Tiago F. Outeiro
Published 2018-08-01

Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.

by Diana F Lázaro, Eva F Rodrigues, Ramona Langohr, Hedieh Shahpasandzadeh, Thales Ribeiro, Patrícia Guerreiro, Ellen Gerhardt, Katharina Kröhnert, Jochen Klucken, Marcos D Pereira, Blagovesta Popova, Niels Kruse, Brit Mollenhauer, Silvio O Rizzoli, Gerhard H Braus, Karin M Danzer, Tiago F Outeiro
Published 2014-11-01

Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies

by Éva M. Szegő, Antonio Dominguez-Meijide, Ellen Gerhardt, Annekatrin König, David J. Koss, Wen Li, Raquel Pinho, Christiane Fahlbusch, Mary Johnson, Patricia Santos, Anna Villar-Piqué, Tobias Thom, Silvio Rizzoli, Matthias Schmitz, Jiayi Li, Inga Zerr, Johannes Attems, Olaf Jahn, Tiago F. Outeiro
Published 2019-07-01

Correction: Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles.

by Raquel Pinho, Leonor C Guedes, Lilach Soreq, Patrícia P Lobo, Tiago Mestre, Miguel Coelho, Mário M Rosa, Nilza Gonçalves, Pauline Wales, Tiago Mendes, Ellen Gerhardt, Christiane Fahlbusch, Vincenzo Bonifati, Michael Bonin, Gabriel Miltenberger-Miltényi, Fran Borovecki, Hermona Soreq, Joaquim J Ferreira, Tiago F Outeiro
Published 2017-01-01

Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles.

by Raquel Pinho, Leonor C Guedes, Lilach Soreq, Patrícia P Lobo, Tiago Mestre, Miguel Coelho, Mário M Rosa, Nilza Gonçalves, Pauline Wales, Tiago Mendes, Ellen Gerhardt, Christiane Fahlbusch, Vincenzo Bonifati, Michael Bonin, Gabriel Miltenberger-Miltényi, Fran Borovecki, Hermona Soreq, Joaquim J Ferreira, Tiago F Outeiro
Published 2016-01-01

Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.

by Rita Machado de Oliveira, Hugo Vicente Miranda, Laetitia Francelle, Raquel Pinho, Éva M Szegö, Renato Martinho, Francesca Munari, Diana F Lázaro, Sébastien Moniot, Patrícia Guerreiro, Luis Fonseca-Ornelas, Zrinka Marijanovic, Pedro Antas, Ellen Gerhardt, Francisco Javier Enguita, Bruno Fauvet, Deborah Penque, Teresa Faria Pais, Qiang Tong, Stefan Becker, Sebastian Kügler, Hilal Ahmed Lashuel, Clemens Steegborn, Markus Zweckstetter, Tiago Fleming Outeiro
Published 2017-04-01

The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.

by Rita Machado de Oliveira, Hugo Vicente Miranda, Laetitia Francelle, Raquel Pinho, Éva M Szegö, Renato Martinho, Francesca Munari, Diana F Lázaro, Sébastien Moniot, Patrícia Guerreiro, Luis Fonseca-Ornelas, Zrinka Marijanovic, Pedro Antas, Ellen Gerhardt, Francisco Javier Enguita, Bruno Fauvet, Deborah Penque, Teresa Faria Pais, Qiang Tong, Stefan Becker, Sebastian Kügler, Hilal Ahmed Lashuel, Clemens Steegborn, Markus Zweckstetter, Tiago Fleming Outeiro
Published 2017-03-01