Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level

by Yannick F. Fuchs, Virag Sharma, Virag Sharma, Anne Eugster, Gloria Kraus, Robert Morgenstern, Andreas Dahl, Susanne Reinhardt, Andreas Petzold, Annett Lindner, Doreen Löbel, Ezio Bonifacio, Ezio Bonifacio, Ezio Bonifacio
Published 2019-11-01

Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice

by Deepika Watts, Deepika Watts, Deepika Watts, Marthe Janßen, Marthe Janßen, Marthe Janßen, Mangesh Jaykar, Francesco Palmucci, Francesco Palmucci, Francesco Palmucci, Marc Weigelt, Cathleen Petzold, Angela Hommel, Tim Sparwasser, Ezio Bonifacio, Ezio Bonifacio, Ezio Bonifacio, Karsten Kretschmer, Karsten Kretschmer, Karsten Kretschmer
Published 2021-08-01

Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection

by Maria Schreiber, Maria Schreiber, Marc Weigelt, Marc Weigelt, Anne Karasinsky, Konstantinos Anastassiadis, Sonja Schallenberg, Cathleen Petzold, Ezio Bonifacio, Ezio Bonifacio, Karsten Kretschmer, Karsten Kretschmer, Angela Hommel, Angela Hommel
Published 2019-04-01

Landmark models to define the age-adjusted risk of developing stage 1 type 1 diabetes across childhood and adolescence

by Verena Sophia Hoffmann, Andreas Weiß, Christiane Winkler, Annette Knopff, Manja Jolink, Ezio Bonifacio, Anette-G. Ziegler
Published 2019-07-01

Role of CCL2/MCP-1 in Islet Transplantation

by Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Elisa Cantarelli, Rita Nano, Paola Maffi, Giovanni Sitia, Luca G. Guidotti, Antonio Secchi, Ezio Bonifacio, Lorenzo Piemonti
Published 2010-08-01

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2

by Nuria Cerdá-Esteban, Heike Naumann, Silvia Ruzittu, Nancy Mah, Igor M. Pongrac, Corinna Cozzitorto, Angela Hommel, Miguel A. Andrade-Navarro, Ezio Bonifacio, Francesca M. Spagnoli
Published 2017-02-01

Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice

by Tanja Telieps, Meike Köhler, Irina Treise, Katharina Foertsch, Thure Adler, Dirk H. Busch, Martin Hrabě de Angelis, Admar Verschoor, Kerstin Adler, Ezio Bonifacio, Anette-Gabriele Ziegler
Published 2016-01-01

Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice.

by Raffaella Melzi, Barbara Antonioli, Alessia Mercalli, Manuela Battaglia, Andrea Valle, Stefano Pluchino, Rossella Galli, Valeria Sordi, Emanuele Bosi, Gianvito Martino, Ezio Bonifacio, Claudio Doglioni, Lorenzo Piemonti
Published 2010-04-01

Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System

by José Manuel Marín Morales, Nadine Münch, Katja Peter, Daniel Freund, Uta Oelschlägel, Kristina Hölig, Thea Böhm, Anne-Christine Flach, Jörg Keßler, Ezio Bonifacio, Martin Bornhäuser, Martin Bornhäuser, Anke Fuchs, Anke Fuchs, Anke Fuchs
Published 2019-02-01

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells

by Joanna Bandoła, Cornelia Richter, Martin Ryser, Arshad Jamal, Arshad Jamal, Michelle P. Ashton, Malte von Bonin, Malte von Bonin, Malte von Bonin, Matthias Kuhn, Benjamin Dorschner, Dimitra Alexopoulou, Katrin Navratiel, Ingo Roeder, Andreas Dahl, Christian M. Hedrich, Ezio Bonifacio, Sebastian Brenner, Sebastian Brenner, Sebastian Thieme
Published 2017-08-01

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.

by Ezio Bonifacio, Andreas Beyerlein, Markus Hippich, Christiane Winkler, Kendra Vehik, Michael N Weedon, Michael Laimighofer, Andrew T Hattersley, Jan Krumsiek, Brigitte I Frohnert, Andrea K Steck, William A Hagopian, Jeffrey P Krischer, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Jorma Toppari, Beena Akolkar, Richard A Oram, Stephen S Rich, Anette-G Ziegler, TEDDY Study Group
Published 2018-04-01

Efficacy of vildagliptin for prevention of postpartum diabetes in women with a recent history of insulin-requiring gestational diabetes: A phase II, randomized, double-blind, place...

by Sandra Hummel, Andreas Beyerlein, Markus Pfirrmann, Anna Hofelich, Daniela Much, Susanne Hivner, Melanie Bunk, Melanie Herbst, Claudia Peplow, Markus Walter, Denise Kohn, Nadine Hummel, Jürgen Kratzsch, Michael Hummel, Martin Füchtenbusch, Joerg Hasford, Anette-G. Ziegler, Markus Walter, Heike Börschmann, Sophia Ebe, Eleni Giannopoulou, Minna Harsunen, Veronika Hofbauer, Anna Hofelich, Andrea Schuppenies, Maike Wallner, David Wiesenäcker, Stephanie Zillmer, Melanie Bunk, Melanie Herbst, Susanne Hivner, Lorenz Lachmann, Daniela Much, Claudia Peplow, Joerg Hasford, Markus Pfirrmann, Rüdiger Landgraf, Karl-Theo Maria Schneider, Elisabeth André, Viktoria Janke, Andreas Beyerlein, Sandra Hummel, Ezio Bonifacio, Martin Füchtenbusch, Michael Hummel, Denise Kohn
Published 2018-03-01