CRISPR/Cas9 System as a Valuable Genome Editing Tool for Wine Yeasts with Application to Decrease Urea Production

by Ileana Vigentini, Marinella Gebbia, Alessandra Belotti, Roberto Foschino, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth
Published 2017-11-01

Absence of evidence for MHC-dependent mate selection within HapMap populations.

by Adnan Derti, Can Cenik, Peter Kraft, Frederick P Roth
Published 2010-04-01

Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background

by Artem Sokolov, Stephanie Ashenden, Stephanie Ashenden, Nil Sahin, Nil Sahin, Richard Lewis, Nurdan Erdem, Elif Ozaltan, Andreas Bender, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth, Murat Cokol, Murat Cokol, Murat Cokol, Murat Cokol
Published 2019-04-01

Protein domain-level landscape of cancer-type-specific somatic mutations.

by Fan Yang, Evangelia Petsalaki, Thomas Rolland, David E Hill, Marc Vidal, Frederick P Roth
Published 2015-03-01

Quantifying immune-based counterselection of somatic mutations.

by Fan Yang, Dae-Kyum Kim, Hidewaki Nakagawa, Shuto Hayashi, Seiya Imoto, Lincoln Stein, Frederick P Roth
Published 2019-07-01

RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins.

by Kohila Mahadevan, Hui Zhang, Abdalla Akef, Xianying A Cui, Serge Gueroussov, Can Cenik, Frederick P Roth, Alexander F Palazzo
Published 2013-01-01

MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect

by Daniel Esposito, Jochen Weile, Jay Shendure, Lea M. Starita, Anthony T. Papenfuss, Frederick P. Roth, Douglas M. Fowler, Alan F. Rubin
Published 2019-11-01

Confirmation of organized modularity in the yeast interactome.

by Nicolas Bertin, Nicolas Simonis, Denis Dupuy, Michael E Cusick, Jing-Dong J Han, Hunter B Fraser, Frederick P Roth, Marc Vidal
Published 2007-06-01

Identifying pathogenicity of human variants via paralog-based yeast complementation.

by Fan Yang, Song Sun, Guihong Tan, Michael Costanzo, David E Hill, Marc Vidal, Brenda J Andrews, Charles Boone, Frederick P Roth
Published 2017-05-01

Modeling the impact of drug interactions on therapeutic selectivity

by Zohar B. Weinstein, Nurdan Kuru, Szilvia Kiriakov, Adam C. Palmer, Ahmad S. Khalil, Paul A. Clemons, Muhammad H. Zaman, Frederick P. Roth, Murat Cokol
Published 2018-08-01

Interpreting metabolomic profiles using unbiased pathway models.

by Rahul C Deo, Luke Hunter, Gregory D Lewis, Guillaume Pare, Ramachandran S Vasan, Daniel Chasman, Thomas J Wang, Robert E Gerszten, Frederick P Roth
Published 2010-02-01

Yeast-Based Genetic Interaction Analysis of Human Kinome

by Jae-Hong Kim, Yeojin Seo, Myungjin Jo, Hyejin Jeon, Won-Ha Lee, Nozomu Yachie, Quan Zhong, Marc Vidal, Frederick P. Roth, Kyoungho Suk
Published 2020-05-01

Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes.

by Can Cenik, Hon Nian Chua, Hui Zhang, Stefan P Tarnawsky, Abdalla Akef, Adnan Derti, Murat Tasan, Melissa J Moore, Alexander F Palazzo, Frederick P Roth
Published 2011-04-01

A genome-wide gene function prediction resource for Drosophila melanogaster.

by Han Yan, Kavitha Venkatesan, John E Beaver, Niels Klitgord, Muhammed A Yildirim, Tong Hao, David E Hill, Michael E Cusick, Norbert Perrimon, Frederick P Roth, Marc Vidal
Published 2010-08-01

A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase

by Song Sun, Jochen Weile, Marta Verby, Yingzhou Wu, Yang Wang, Atina G. Cote, Iosifina Fotiadou, Julia Kitaygorodsky, Marc Vidal, Jasper Rine, Pavel Ješina, Viktor Kožich, Frederick P. Roth
Published 2020-01-01

Systematic identification of phosphorylation-mediated protein interaction switches.

by Matthew J Betts, Oliver Wichmann, Mathias Utz, Timon Andre, Evangelia Petsalaki, Pablo Minguez, Luca Parca, Frederick P Roth, Anne-Claude Gavin, Peer Bork, Robert B Russell, Robert B Russell
Published 2017-03-01

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

by Melissa A Chiasson, Nathan J Rollins, Jason J Stephany, Katherine A Sitko, Kenneth A Matreyek, Marta Verby, Song Sun, Frederick P Roth, Daniel DeSloover, Debora S Marks, Allan E Rettie, Douglas M Fowler
Published 2020-09-01

CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

by Eric Deneault, Muhammad Faheem, Sean H White, Deivid C Rodrigues, Song Sun, Wei Wei, Alina Piekna, Tadeo Thompson, Jennifer L Howe, Leon Chalil, Vickie Kwan, Susan Walker, Peter Pasceri, Frederick P Roth, Ryan KC Yuen, Karun K Singh, James Ellis, Stephen W Scherer
Published 2019-02-01

A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions

by Dae-Kyum Kim, Jennifer J. Knapp, Da Kuang, Aditya Chawla, Patricia Cassonnet, Hunsang Lee, Dayag Sheykhkarimli, Payman Samavarchi-Tehrani, Hala Abdouni, Ashyad Rayhan, Roujia Li, Oxana Pogoutse, Étienne Coyaud, Sylvie van der Werf, Caroline Demeret, Anne-Claude Gingras, Mikko Taipale, Brian Raught, Yves Jacob, Frederick P. Roth
Published 2020-09-01

Systematic analysis of bypass suppression of essential genes

by Jolanda vanLeeuwen, Carles Pons, Guihong Tan, Jason Zi Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha vanLieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone
Published 2020-09-01