The epithelial αvβ3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.

by Tatiana Gianni, Gabriella Campadelli-Fiume
Published 2014-11-01

Human Herpesvirus 6: An Emerging Pathogen

by Gabriella Campadelli-Fiume, Prisco Mirandola, Laura Menotti
Published 1999-06-01

The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its Receptors.

by Valentina Gatta, Valentina Gatta, Biljana Petrovic, Gabriella Campadelli-Fiume
Published 2015-05-01

Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.

by Biljana Petrovic, Tatiana Gianni, Valentina Gatta, Valentina Gatta, Gabriella Campadelli-Fiume
Published 2017-04-01

HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

by Laura Menotti, Elisa Avitabile, Valentina Gatta, Paolo Malatesta, Biljana Petrovic, Gabriella Campadelli-Fiume
Published 2018-06-01

αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion.

by Tatiana Gianni, Stefano Salvioli, Liudmila S Chesnokova, Lindsey M Hutt-Fletcher, Gabriella Campadelli-Fiume
Published 2013-01-01

Immunotherapeutic Efficacy of Retargeted oHSVs Designed for Propagation in an Ad Hoc Cell Line

by Andrea Vannini, Valerio Leoni, Mara Sanapo, Tatiana Gianni, Giorgia Giordani, Valentina Gatta, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume
Published 2021-01-01

Genotype of Immunologically Hot or Cold Tumors Determines the Antitumor Immune Response and Efficacy by Fully Virulent Retargeted oHSV

by Tatiana Gianni, Valerio Leoni, Mara Sanapo, Federico Parenti, Daniela Bressanin, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume, Andrea Vannini
Published 2021-09-01

Specificity, Safety, Efficacy of EGFRvIII-Retargeted Oncolytic HSV for Xenotransplanted Human Glioblastoma

by Irene Appolloni, Francesco Alessandrini, Laura Menotti, Elisa Avitabile, Daniela Marubbi, Noemi Piga, Davide Ceresa, Francesca Piaggio, Gabriella Campadelli-Fiume, Paolo Malatesta
Published 2021-08-01

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors.

by Valerio Leoni, Andrea Vannini, Valentina Gatta, Julie Rambaldi, Mara Sanapo, Catia Barboni, Anna Zaghini, Patrizia Nanni, Pier-Luigi Lollini, Costanza Casiraghi, Gabriella Campadelli-Fiume
Published 2018-08-01

Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.

by Patrizia Nanni, Valentina Gatta, Valentina Gatta, Laura Menotti, Carla De Giovanni, Marianna Ianzano, Arianna Palladini, Valentina Grosso, Massimiliano Dall'ora, Stefania Croci, Giordano Nicoletti, Lorena Landuzzi, Manuela Iezzi, Gabriella Campadelli-Fiume, Pier-Luigi Lollini
Published 2013-01-01

Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment

by Maria De Lucia, Gabriella Cotugno, Veronica Bignone, Irene Garzia, Linda Nocchi, Francesca Langone, Biljana Petrovic, Emanuele Sasso, Simona Pepe, Guendalina Froechlich, Chiara Gentile, Nicola Zambrano, Gabriella Campadelli-Fiume, Alfredo Nicosia, Elisa Scarselli, Anna Morena D’Alise
Published 2020-12-01