Tumor suppressive Ca2+ signaling is driven by IP3 receptor fitness

by Geert Bultynck, Michelangelo Campanella
Published 2017-11-01

Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound

by Mart Bittremieux, Katsuhiko Mikoshiba, Geert Bultynck
Published 2017-06-01

Editorial: Inter-Organelle Calcium Communication in Cancer

by Cesar Cardenas, Cesar Cardenas, Cesar Cardenas, Cesar Cardenas, Paolo Pinton, Paolo Pinton, Geert Bultynck, Geert Bultynck
Published 2018-02-01

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

by Geert Bultynck, Jan B. Parys, Jean-Paul Decuypere
Published 2012-07-01

Endoplasmic Reticulum–Mitochondrial Ca2+ Fluxes Underlying Cancer Cell Survival

by Hristina Ivanova, Martijn Kerkhofs, Rita M. La Rovere, Geert Bultynck
Published 2017-05-01

IP3 Receptor-Mediated Calcium Signaling and Its Role in Autophagy in Cancer

by Elzbieta Kania, Gemma Roest, Tim Vervliet, Jan B. Parys, Geert Bultynck
Published 2017-07-01

Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?

by Marijke De Bock, Nan Wang, Elke Decrock, Geert Bultynck, Luc Leybaert
Published 2015-01-01

Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum–Mitochondrial Interface

by Tim Vervliet, Eva Clerix, Bruno Seitaj, Hristina Ivanova, Giovanni Monaco, Geert Bultynck
Published 2017-05-01

DLBCL Cells with Acquired Resistance to Venetoclax Are Not Sensitized to BIRD-2 But Can Be Resensitized to Venetoclax through Bcl-XL Inhibition

by Martijn Kerkhofs, Tamara Vervloessem, Kinga B. Stopa, Victoria M. Smith, Meike Vogler, Geert Bultynck
Published 2020-07-01

The ER Stress Inducer <span style="font-variant: small-caps">l</span>-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca²⁺-Dependent...

by Gemma Roest, Evelien Hesemans, Kirsten Welkenhuyzen, Tomas Luyten, Nikolai Engedal, Geert Bultynck, Jan B. Parys
Published 2018-11-01

IP3 Receptors, Mitochondria, and Ca2+ Signaling: Implications for Aging

by Jean-Paul Decuypere, Giovanni Monaco, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys, Geert Bultynck
Published 2011-01-01

RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system.

by Raf Ponsaerts, Catheleyne D'hondt, Fréderic Hertens, Jan B Parys, Luc Leybaert, Johan Vereecke, Bernard Himpens, Geert Bultynck
Published 2012-01-01

mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.

by Jean-Paul Decuypere, Dimphny Kindt, Tomas Luyten, Kirsten Welkenhuyzen, Ludwig Missiaen, Humbert De Smedt, Geert Bultynck, Jan B Parys
Published 2013-01-01

Corrigendum to “Superoxide Anion Production and Bioenergetic Profile in Young and Elderly Human Primary Myoblasts”

by Mariangela Marrone, Rita Maria Laura La Rovere, Simone Guarnieri, Ester Sara Di Filippo, Giovanni Monaco, Tiziana Pietrangelo, Geert Bultynck, Stefania Fulle, Rosa Mancinelli
Published 2021-01-01

Synthesis and in vitro evaluation of dioxopyrrolopyrroles as potential low-affinity fluorescent Ca2+ indicators

by Nesibe Avcıbaşi, Mario Smet, Bert Metten, Wim Dehaen, Frans C. De Schryver, Geert Bultynck, Geert Callewaert, Humbert De Smedt, Ludwig Missiaen, Noël Boens
Published 2004-01-01

Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery

by Bruno Seitaj, Felicia Maull, Li Zhang, Verena Wüllner, Christina Wolf, Philipp Schippers, Rita La Rovere, Ute Distler, Stefan Tenzer, Jan B. Parys, Geert Bultynck, Axel Methner
Published 2020-09-01

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

by Jenny Sprooten, Pieter De Wijngaert, Isaure Vanmeerbeerk, Shaun Martin, Peter Vangheluwe, Susan Schlenner, Dmitri V. Krysko, Jan B. Parys, Geert Bultynck, Peter Vandenabeele, Abhishek D. Garg
Published 2020-08-01

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings

by Giampaolo Morciano, Saverio Marchi, Claudia Morganti, Luigi Sbano, Mart Bittremieux, Martijn Kerkhofs, Mariangela Corricelli, Alberto Danese, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski, Geert Bultynck, Carlotta Giorgi, Paolo Pinton
Published 2018-05-01

Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor.

by Giovanni Monaco, Elke Decrock, Koen Nuyts, Larry E Wagner, Tomas Luyten, Sergei V Strelkov, Ludwig Missiaen, Wim M De Borggraeve, Luc Leybaert, David I Yule, Humbert De Smedt, Jan B Parys, Geert Bultynck
Published 2013-01-01

Dominant mutations in ITPR3 cause Charcot‐Marie‐Tooth disease

by Julius Rönkkö, Svetlana Molchanova, Anya Revah‐Politi, Elaine M. Pereira, Mari Auranen, Jussi Toppila, Jouni Kvist, Anastasia Ludwig, Julika Neumann, Geert Bultynck, Stéphanie Humblet‐Baron, Adrian Liston, Anders Paetau, Claudio Rivera, Matthew B. Harms, Henna Tyynismaa, Emil Ylikallio
Published 2020-10-01