Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300: response to correspondence by Borzì et al.

by Pradeep K. Sacitharan, George Bou Gharios, James R. Edwards
Published 2019-03-01

Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300

by Pradeep K. Sacitharan, Seint Lwin, George Bou Gharios, James R. Edwards
Published 2018-09-01

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis

by Hiroyuki Nakamura, Phoung Vo, Ioannis Kanakis, Ke Liu, George Bou-Gharios
Published 2020-06-01

Distant mesenchymal progenitors contribute to skin wound healing and produce collagen: evidence from a murine fetal microchimerism model.

by Elke Seppanen, Edwige Roy, Rebecca Ellis, George Bou-Gharios, Nicholas M Fisk, Kiarash Khosrotehrani
Published 2013-01-01

The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within?

by Behzad Javaheri, Soraia P. Caetano-Silva, Ioannis Kanakis, George Bou-Gharios, Andrew A. Pitsillides
Published 2018-03-01

Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2‐dioxygenase deficiency in the liver is responsible for homogentisic acid‐derived ochronotic pigme...

by Peter J. M. Wilson, Lakshminarayan R. Ranganath, George Bou‐Gharios, James A. Gallagher, Juliette H. Hughes
Published 2021-03-01

Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis

by Lorenzo Ramos-Mucci, Behzad Javaheri, Rob van ‘t Hof, George Bou-Gharios, Andrew A. Pitsillides, Eithne Comerford, Blandine Poulet
Published 2020-07-01

Syndecan 3 stimulates bone formation through stabilisation of Frizzled 1

by Andrew Butcher, Gemma Charlesworth, Amanda Prior, Katherine Sperinck, Adolorata Pisconti, George Bou-Gharios, Anna Daroszewska, Rob Van ’THof
Published 2020-10-01

Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2

by Craig M. Keenan, Lorenzo Ramos-Mucci, Ioannis Kanakis, Peter I. Milner, Andrew Leask, David Abraham, George Bou-Gharios, Blandine Poulet
Published 2020-07-01

Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo.

by Behzad Javaheri, Mark Hopkinson, Blandine Poulet, Andrea S Pollard, Sandra J Shefelbine, Yu-Mei Chang, Philippa Francis-West, George Bou-Gharios, Andrew A Pitsillides
Published 2016-01-01

Data on CUX1 isoforms in idiopathic pulmonary fibrosis lung and systemic sclerosis skin tissue sections

by Tetsurou Ikeda, Maria Fragiadaki, Xu Shi-wen, Markella Ponticos, Korsa Khan, Christopher Denton, Patricia Garcia, George Bou-Gharios, Akio Yamakawa, Chikao Morimoto, David Abraham
Published 2016-09-01

Heat shock protein B1-deficient mice display impaired wound healing.

by Jonathan Crowe, Anna Aubareda, Kay McNamee, Paulina M Przybycien, Xin Lu, Richard O Williams, George Bou-Gharios, Jeremy Saklatvala, Jonathan L E Dean
Published 2013-01-01

Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity.

by Blandine Poulet, Ke Liu, Darren Plumb, Phoung Vo, Mittal Shah, Katherine Staines, Alexandra Sampson, Hiroyuki Nakamura, Hideaki Nagase, Alessandra Carriero, Sandra Shefelbine, Andrew A Pitsillides, George Bou-Gharios
Published 2016-01-01

Ontological differences in first compared to third trimester human fetal placental chorionic stem cells.

by Gemma N Jones, Dafni Moschidou, Tamara-Isabel Puga-Iglesias, Katarzyna Kuleszewicz, Maximilien Vanleene, Sandra J Shefelbine, George Bou-Gharios, Nicholas M Fisk, Anna L David, Paolo De Coppi, Pascale V Guillot
Published 2012-01-01

Venous identity requires BMP signalling through ALK3

by Alice Neal, Svanhild Nornes, Sophie Payne, Marsha D. Wallace, Martin Fritzsche, Pakavarin Louphrasitthiphol, Robert N. Wilkinson, Kira M. Chouliaras, Ke Liu, Karen Plant, Radhika Sholapurkar, Indrika Ratnayaka, Wiebke Herzog, Gareth Bond, Tim Chico, George Bou-Gharios, Sarah De Val
Published 2019-01-01