The NR4A2 nuclear receptor is recruited to novel nuclear foci in response to UV irradiation and participates in nucleotide excision repair.

by Kasturee Jagirdar, Kelvin Yin, Matthew Harrison, Wen Lim, George E O Muscat, Richard A Sturm, Aaron G Smith
Published 2013-01-01

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control

by Zewen Kelvin Tuong, Rebecca Fitzsimmons, Shu-Ching Mary Wang, Tae Gyu Oh, Patrick Lau, Frederik Steyn, Gethin Thomas, George E.O. Muscat
Published 2016-09-01

RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages.

by Zewen Kelvin Tuong, Patrick Lau, Ximing Du, Nicholas D Condon, Joel M Goode, Tae Gyu Oh, Jeremy C Yeo, George E O Muscat, Jennifer L Stow
Published 2016-01-01

A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cance...

by Tram B. Doan, Vanessa Cheung, Colin D. Clyne, Heidi N. Hilton, Natalie Eriksson, Morag J. Young, John W. Funder, George E. O. Muscat, Peter J. Fuller, Christine L. Clarke, J. Dinny Graham
Published 2020-11-01

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF

by Mitchell E. Fane, Yash Chhabra, David E.J. Hollingsworth, Jacinta L. Simmons, Loredana Spoerri, Tae Gyu Oh, Jagat Chauhan, Toby Chin, Lachlan Harris, Tracey J. Harvey, George E.O. Muscat, Colin R. Goding, Richard A Sturm, Nikolas K. Haass, Glen M. Boyle, Michael Piper, Aaron G. Smith
Published 2017-02-01

Caveolin-1 Is Necessary for Hepatic Oxidative Lipid Metabolism: Evidence for Crosstalk between Caveolin-1 and Bile Acid Signaling

by Manuel A. Fernández-Rojo, Milena Gongora, Rebecca L. Fitzsimmons, Nick Martel, Sheree D. Martin, Susan J. Nixon, Andrew J. Brooks, Maria P. Ikonomopoulou, Sally Martin, Harriet P. Lo, Stephen A. Myers, Christina Restall, Charles Ferguson, Paul F. Pilch, Sean L. McGee, Robin L. Anderson, Michael J. Waters, John F. Hancock, Sean M. Grimmond, George E.O. Muscat, Robert G. Parton
Published 2013-07-01