Tetherin downmodulation by SIVmac Nef lost with the H196Q escape variant is restored by an upstream variant.

by Blake Schouest, George J Leslie, James A Hoxie, Nicholas J Maness
Published 2020-01-01

V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies.

by Meg M Laakso, Fang-Hua Lee, Beth Haggarty, Caroline Agrawal, Katrina M Nolan, Mark Biscone, Josephine Romano, Andrea P O Jordan, George J Leslie, Eric G Meissner, Lishan Su, James A Hoxie, Robert W Doms
Published 2007-08-01

Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.

by George J Leslie, Jianbin Wang, Max W Richardson, Beth S Haggarty, Kevin L Hua, Jennifer Duong, Anthony J Secreto, Andrea P O Jordon, Josephine Romano, Kritika E Kumar, Joshua J DeClercq, Philip D Gregory, Carl H June, Michael J Root, James L Riley, Michael C Holmes, James A Hoxie
Published 2016-11-01