Uncovering critical properties of the human respiratory syncytial virus by combining in vitro assays and in silico analyses.

by Catherine A A Beauchemin, Young-In Kim, Qin Yu, Giuseppe Ciaramella, John P DeVincenzo
Published 2019-01-01

Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

by Yi Yu, Thomas C. Leete, David A. Born, Lauren Young, Luis A. Barrera, Seung-Joo Lee, Holly A. Rees, Giuseppe Ciaramella, Nicole M. Gaudelli
Published 2020-04-01

111 Highly efficient multiplexed base editing enables development of universal CD7-targeting CAR-T Cells to treat T-ALL

by Sarah Smith, Alden Ladd, Jason Gehrke, Aaron Edwards, Ryan Murray, Angelica Messana, Lindsey Coholan, Henry Poulin, Melissa Le, Mark Naniong, Faith Musenge, Adam Camblin, Yeh-Chuin Poh, Giuseppe Ciaramella
Published 2020-11-01

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

by Claude Roth, Claude Roth, Tineke Cantaert, Chloé Colas, Chloé Colas, Matthieu Prot, Matthieu Prot, Isabelle Casadémont, Isabelle Casadémont, Laurine Levillayer, Laurine Levillayer, Jessie Thalmensi, Pierre Langlade-Demoyen, Christiane Gerke, Kapil Bahl, Giuseppe Ciaramella, Etienne Simon-Loriere, Etienne Simon-Loriere, Anavaj Sakuntabhai, Anavaj Sakuntabhai
Published 2019-06-01

HIV capsid is a tractable target for small molecule therapeutic intervention.

by Wade S Blair, Chris Pickford, Stephen L Irving, David G Brown, Marie Anderson, Richard Bazin, Joan Cao, Giuseppe Ciaramella, Jason Isaacson, Lynn Jackson, Rachael Hunt, Anne Kjerrstrom, James A Nieman, Amy K Patick, Manos Perros, Andrew D Scott, Kevin Whitby, Hua Wu, Scott L Butler
Published 2010-01-01

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

by Kimberly J. Hassett, Kerry E. Benenato, Eric Jacquinet, Aisha Lee, Angela Woods, Olga Yuzhakov, Sunny Himansu, Jessica Deterling, Benjamin M. Geilich, Tatiana Ketova, Cosmin Mihai, Andy Lynn, Iain McFadyen, Melissa J. Moore, Joseph J. Senn, Matthew G. Stanton, Örn Almarsson, Giuseppe Ciaramella, Luis A. Brito
Published 2019-04-01

Corrigendum: Induction of Robust B Cell Responses After Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

by Gustaf Lindgren, Gustaf Lindgren, Sebastian Ols, Sebastian Ols, Frank Liang, Frank Liang, Elizabeth A. Thompson, Elizabeth A. Thompson, Ang Lin, Ang Lin, Fredrika Hellgren, Fredrika Hellgren, Kapil Bahl, Shinu John, Olga Yuzhakov, Kimberly J. Hassett, Luis A. Brito, Hugh Salter, Hugh Salter, Giuseppe Ciaramella, Karin Loré, Karin Loré
Published 2019-04-01

Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

by Gustaf Lindgren, Gustaf Lindgren, Sebastian Ols, Sebastian Ols, Frank Liang, Frank Liang, Elizabeth A. Thompson, Elizabeth A. Thompson, Ang Lin, Ang Lin, Fredrika Hellgren, Fredrika Hellgren, Kapil Bahl, Shinu John, Olga Yuzhakov, Kimberly J. Hassett, Luis A. Brito, Hugh Salter, Hugh Salter, Giuseppe Ciaramella, Karin Loré, Karin Loré
Published 2017-11-01