The therapeutic importance of understanding mechanisms of neuronal cell death in neurodegenerative disease

by Golde Todd E
Published 2009-02-01

"What kills neurons in neurodegenerative diseases?", a review series in an open access journal

by Petrucelli Leonard, Golde Todd E
Published 2009-02-01

Zoom in on neurodegeneration

by Bu Guojun, Xu Huaxi, Golde Todd E
Published 2006-06-01

Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo

by Das Pritam, Ceballos-Diaz Carolina, Herring Amanda, Chakrabarty Paramita, Golde Todd E
Published 2011-02-01

Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice

by Chu Jin, Giannopoulos Phillip F, Ceballos-Diaz Carolina, Golde Todd E, Pratico Domenico
Published 2012-01-01

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition

by Chakrabarty Paramita, Tianbai Li, Herring Amanda, Ceballos-Diaz Carolina, Das Pritam, Golde Todd E
Published 2012-07-01

Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel γ-secretase substrates

by Nyborg Andrew C, Ladd Thomas B, Zwizinski Craig W, Lah James J, Golde Todd E
Published 2006-06-01

Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy

by Chakrabarty Paramita, Levites Yona, Holloway Vallie M, Price Robert W, Smithson Lisa A, Das Pritam, Golde Todd E
Published 2006-07-01

Signal peptide peptidase (SPP) dimer formation as assessed by fluorescence lifetime imaging microscopy (FLIM) in intact cells

by Nyborg Andrew C, Herl Lauren, Berezovska Oksana, Thomas Anne V, Ladd Thomas B, Jansen Karen, Hyman Bradley T, Golde Todd E
Published 2006-11-01

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice

by Koo Edward H, Murphy M Paul, Holloway Vallie, Eriksen Jason L, Prescott Sonya, Kukar Thomas, Golde Todd E, Nicolle Michelle M
Published 2007-07-01

Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575

by Golde Todd E, Das Pritam, Fauq Abdul, Borrelli Laura A, Thyssen Diana, Subramanian Meenakshi, Garcia-Alloza Monica, Hyman Bradley T, Bacskai Brian J
Published 2009-05-01

Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology

by Das Pritam, Verbeeck Christophe, Minter Lisa, Chakrabarty Paramita, Felsenstein Kevin, Kukar Thomas, Maharvi Ghulam, Fauq Abdul, Osborne Barbara A, Golde Todd E
Published 2012-08-01

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels

by Dicker Bridget L, Smithson Lisa, Holloway Vallie, Price Robert W, Das Pritam, Bland Ross J, Lawlor Patricia A, During Matthew J, Young Deborah, Golde Todd E
Published 2007-06-01