The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing.

by Da Cheng Hao, GuangBo Ge, PeiGen Xiao, YanYan Zhang, Ling Yang
Published 2011-01-01

In vitro evaluation of the effect of C-4 substitution on methylation of 7,8-dihydroxycoumarin: metabolic profile and catalytic kinetics

by Yang-Liu Xia, Tong-Yi Dou, Yong Liu, Ping Wang, Guang-Bo Ge, Ling Yang
Published 2018-01-01

Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu

by Zi-Ru Dai, Jing Ning, Gui-Bo Sun, Ping Wang, Feng Zhang, Hong-Ying Ma, Li-Wei Zou, Jie Hou, Jing-Jing Wu, Guang-Bo Ge, Guang-Bo Ge, Xiao-Bo Sun, Ling Yang
Published 2019-02-01

Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1

by Li-Wei Zou, Li-Wei Zou, Tong-Yi Dou, Ping Wang, Ping Wang, Wei Lei, Wei Lei, Zi-Miao Weng, Jie Hou, Dan-Dan Wang, Yi-Ming Fan, Wei-Dong Zhang, Guang-Bo Ge, Guang-Bo Ge, Ling Yang
Published 2017-06-01

Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2

by Yun-Qing Song, Yun-Qing Song, Rong-Jing He, Dan Pu, Dan Pu, Xiao-Qing Guan, Jin-Hui Shi, Yao-Guang Li, Jie Hou, Shou-Ning Jia, Wei-Wei Qin, Wei-Wei Qin, Sheng-Quan Fang, Guang-Bo Ge, Guang-Bo Ge
Published 2021-05-01

Analytical methodologies for sensing catechol-O-methyltransferase activity and their applications

by Fang-Yuan Wang, Ping Wang, Dong-Fang Zhao, Frank J. Gonzalez, Yu-Fan Fan, Yang-Liu Xia, Guang-Bo Ge, Ling Yang
Published 2021-02-01

Inhibition of human carboxylesterases by ginsenosides: structure–activity relationships and inhibitory mechanism

by Zhao-Hui Sun, Jing Chen, Yun-Qing Song, Tong-Yi Dou, Li-Wei Zou, Da-Cheng Hao, Hai-Bin Liu, Guang-Bo Ge, Ling Yang
Published 2019-12-01

A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4

by Zi-Ru Dai, Chun-Zhi Ai, Guang-Bo Ge, Yu-Qi He, Jing-Jing Wu, Jia-Yue Wang, Hui-Zi Man, Yan Jia, Ling Yang
Published 2015-06-01

Spectrophotometric Assays for Sensing Tyrosinase Activity and Their Applications

by Yu-Fan Fan, Si-Xing Zhu, Fan-Bin Hou, Dong-Fang Zhao, Qiu-Sha Pan, Yan-Wei Xiang, Xing-Kai Qian, Guang-Bo Ge, Ping Wang
Published 2021-08-01

Neobavaisoflavone Induces Bilirubin Metabolizing Enzyme UGT1A1 via PPARα and PPARγ

by Ya-Di Zhu, Xiao-Qing Guan, Jing Chen, Sheng Peng, Moshe Finel, Ying-Yuan Zhao, Rui-Min Wang, Hui-Chang Bi, Ming Lei, Dan-Dan Wang, Guang-Bo Ge
Published 2021-02-01

An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

by Ya-Di Zhu, Hui-Lin Pang, Qi-Hang Zhou, Zi-Fei Qin, Qiang Jin, Moshe Finel, Yi-Nan Wang, Wei-Wei Qin, Yin Lu, Dan-Dan Wang, Guang-Bo Ge
Published 2020-06-01

Discovery and characterization of pentacyclic triterpenoid acids in Styrax as potent and reversible pancreatic lipase inhibitors

by Lu Wang, Xiao-Qing Guan, Rong-jing He, Peng-Chao Huo, Wei-Wei Qin, Long-Tao Cui, Qing Hu, Jie Hou, Mihreay Mamat, Shou-Ning Jia, Hui Tang, Guang-Bo Ge
Published 2020-11-01

A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders[S]

by Zhong-Ze Fang, Rong-Rong He, Yun-Feng Cao, Naoki Tanaka, Changtao Jiang, Kristopher W. Krausz, Yunpeng Qi, Pei-Pei Dong, Chun-Zhi Ai, Xiao-Yu Sun, Mo Hong, Guang-Bo Ge, Frank J. Gonzalez, Xiao-Chi Ma, Hong-Zhi Sun
Published 2013-12-01

Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas

by Dieter M. Matlac, Katerina Hadrava Vanova, Katerina Hadrava Vanova, Nicole Bechmann, Susan Richter, Julica Folberth, Hans K. Ghayee, Guang-Bo Ge, Luma Abunimer, Robert Wesley, Redouane Aherrahrou, Redouane Aherrahrou, Margo Dona, Ángel M. Martínez-Montes, Bruna Calsina, Maria J. Merino, Markus Schwaninger, Peter M. T. Deen, Zhengping Zhuang, Jiri Neuzil, Jiri Neuzil, Karel Pacak, Hendrik Lehnert, Stephanie M. J. Fliedner
Published 2021-03-01