Bioinformatic Analyses of miRNA–mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation

by Luiza Ghila, Yngvild Bjørlykke, Thomas Aga Legøy, Heidrun Vethe, Kenichiro Furuyama, Simona Chera, Helge Ræder
Published 2020-06-01

Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells

by Heidrun Vethe, Yngvild Bjørlykke, Luiza M. Ghila, Joao A. Paulo, Hanne Scholz, Steven P. Gygi, Simona Chera, Helge Ræder
Published 2017-07-01

Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability

by Yngvild Bjørlykke, Anne M. Søviknes, Laurence Hoareau, Heidrun Vethe, Andreas F. Mathisen, Simona Chera, Marc Vaudel, Luiza M. Ghila, Helge Ræder
Published 2019-01-01

Novel protein signatures suggest progression to muscular invasiveness in bladder cancer.

by Magnus Berle, Luiza Ghila, Heidrun Vethe, Adeel Chaudhry, Hilde Garberg, Christian Beisland, Øystein Ariansen Haaland, Eystein Oveland, Ole Johan Halvorsen, Thomas Davidsson, Simona Chera
Published 2018-01-01

The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation

by Heidrun Vethe, Luiza Ghila, Magnus Berle, Magnus Berle, Laurence Hoareau, Øystein A. Haaland, Hanne Scholz, Hanne Scholz, Joao A. Paulo, Simona Chera, Helge Ræder, Helge Ræder
Published 2019-05-01

In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism

by Thomas Aga Legøy, Andreas F. Mathisen, Zaidon Salim, Heidrun Vethe, Yngvild Bjørlykke, Shadab Abadpour, Shadab Abadpour, Joao A. Paulo, Hanne Scholz, Hanne Scholz, Helge Ræder, Helge Ræder, Luiza Ghila, Simona Chera
Published 2020-02-01

Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor

by Tomoko Okuyama, Jun Shirakawa, Kazuki Tajima, Yoko Ino, Heidrun Vethe, Yu Togashi, Mayu Kyohara, Ryota Inoue, Daisuke Miyashita, Jinghe Li, Nozomi Goto, Taiga Ichikawa, Shingo Yamasaki, Haruka Ohnuma, Rie Takayanagi, Yayoi Kimura, Hisashi Hirano, Yasuo Terauchi
Published 2020-10-01