Interaction of circulating GLP-1 and the response of the dorsolateral prefrontal cortex to food-cues predicts body weight development

by Lukas Maurer, Knut Mai, Heiko Krude, John-Dylan Haynes, Martin Weygandt, Joachim Spranger
Published 2019-11-01

A New Mechanism in THRA Resistance: The First Disease-Associated Variant Leading to an Increased Inhibitory Function of THRA2

by Sarah Paisdzior, Ellen Knierim, Gunnar Kleinau, Heike Biebermann, Heiko Krude, Rachel Straussberg, Markus Schuelke
Published 2021-05-01

Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists.

by Gunnar Kleinau, Juliane Pratzka, Daniela Nürnberg, Annette Grüters, Dagmar Führer-Sakel, Heiko Krude, Josef Köhrle, Torsten Schöneberg, Heike Biebermann
Published 2011-01-01

The paediatric Confusion Assessment Method for the Intensive Care Unit (pCAM-ICU): Translation and cognitive debriefing for the German-speaking area

by Clemens de Grahl, Alawi Luetz, Alexander Gratopp, Dennis Gensel, Judith Mueller, Heidi Smith, E. Wesley Ely, Heiko Krude, Claudia Spies
Published 2012-04-01

Differential Signaling Profiles of MC4R Mutations with Three Different Ligands

by Sarah Paisdzior, Ioanna Maria Dimitriou, Paul Curtis Schöpe, Paolo Annibale, Patrick Scheerer, Heiko Krude, Martin J. Lohse, Heike Biebermann, Peter Kühnen
Published 2020-02-01

An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity.

by Peter Kuehnen, Mona Mischke, Susanna Wiegand, Christine Sers, Bernhard Horsthemke, Susanne Lau, Thomas Keil, Young-Ae Lee, Annette Grueters, Heiko Krude
Published 2012-01-01

G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.

by Anne Müller, Gunnar Kleinau, Carolin L Piechowski, Timo D Müller, Brian Finan, Juliane Pratzka, Annette Grüters, Heiko Krude, Matthias Tschöp, Heike Biebermann
Published 2013-01-01

Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective

by Nicolas Heyder, Gunnar Kleinau, Michal Szczepek, Dennis Kwiatkowski, David Speck, Lucia Soletto, José Miguel Cerdá-Reverter, Heiko Krude, Peter Kühnen, Heike Biebermann, Patrick Scheerer
Published 2019-07-01

Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5.

by Juliane Dinter, Jessica Mühlhaus, Carolin Leonie Wienchol, Chun-Xia Yi, Daniela Nürnberg, Silke Morin, Annette Grüters, Josef Köhrle, Torsten Schöneberg, Matthias Tschöp, Heiko Krude, Gunnar Kleinau, Heike Biebermann
Published 2015-01-01

Ring finger protein 11 inhibits melanocortin 3 and 4 receptor signaling

by Anne Müller, Lars Niederstadt, Wenke Jonas, Wenke Jonas, Chun-Xia Yi, Franziska Meyer, Petra Wiedmer, Jana Fischer, Carsten Grötzinger, Annette Schürmann, Annette Schürmann, Matthias Tschöp, Matthias Tschöp, Gunnar Kleinau, Annette Grüters, Heiko Krude, Heike Biebermann
Published 2016-08-01

Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1

by Jessica Mühlhaus, Juliane Dinter, Sabine Jyrch, Alexander Teumer, Simon F. Jacobi, Georg Homuth, Peter Kühnen, Susanna Wiegand, Annette Grüters, Henry Völzke, Henry Völzke, Klemens Raile, Klemens Raile, Gunnar Kleinau, Gunnar Kleinau, Heiko Krude, Heike Biebermann
Published 2017-11-01

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

by André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla I G Vogel, Timo D Müller, Harald Grallert, H-Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo-Riitta Jarvelin, Anna-Liisa Hartikainen, Claire Levy-Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kiess, Peter Kovacs, Nigel W Rayner, Inga Prokopenko, Mark I McCarthy, Helmut Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M Nöthen, Thomas W Mühleisen, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, David Meyre
Published 2010-04-01

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

by Iris M Heid, Cornelia Huth, Ruth J F Loos, Florian Kronenberg, Vera Adamkova, Sonia S Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A Cooper, Dolores Corella, Christian Dina, James C Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A Hegele, Anke Hinney, Margret R Hoehe, Frank B Hu, Jaroslav A Hubacek, Steve E Humphries, Steven C Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N Lyon, David Meyre, Karen L Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S Vimaleswaran, Nicholas J Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I McCarthy, Christoph Lange, Joel N Hirschhorn, Nan Laird, H-Erich Wichmann
Published 2009-10-01