Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors

by Andreas Hermann, Jeong Beom Kim, Sumitra Srimasorn, Holm Zaehres, Peter Reinhardt, Hans R. Schöler, Alexander Storch
Published 2016-01-01

Nydus One Syringe Extruder (NOSE): A Prusa i3 3D printer conversion for bioprinting applications utilizing the FRESH-method

by Nils Bessler, Dennis Ogiermann, Maj-Britt Buchholz, Alexander Santel, Jan Heidenreich, Rawas Ahmmed, Holm Zaehres, Beate Brand-Saberi
Published 2019-10-01

bHLH Transcription Factor Math6 Antagonizes TGF-β Signalling in Reprogramming, Pluripotency and Early Cell Fate Decisions

by Satya Srirama Karthik Divvela, Patrick Nell, Markus Napirei, Holm Zaehres, Jiayu Chen, Wanda Maria Gerding, Huu Phuc Nguyen, Shaorong Gao, Beate Brand-Saberi
Published 2019-06-01

FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling

by Jonathan Arias-Fuenzalida, Javier Jarazo, Xiaobing Qing, Jonas Walter, Gemma Gomez-Giro, Sarah Louise Nickels, Holm Zaehres, Hans Robert Schöler, Jens Christian Schwamborn
Published 2017-11-01

Novel Tools towards Magnetic Guidance of Neurite Growth: (I) Guidance of Magnetic Nanoparticles into Neurite Extensions of Induced Human Neurons and In Vitro Functionalization with...

by Hendrik Schöneborn, Fabian Raudzus, Emilie Secret, Nils Otten, Aude Michel, Jérome Fresnais, Christine Ménager, Jean-Michel Siaugue, Holm Zaehres, Irmgard D. Dietzel, Rolf Heumann
Published 2019-07-01

Reprogramming to pluripotency through a somatic stem cell intermediate.

by Adele G Marthaler, Ulf Tiemann, Marcos J Araúzo-Bravo, Guangming Wu, Holm Zaehres, Jung Keun Hyun, Dong Wook Han, Hans R Schöler, Natalia Tapia
Published 2013-01-01

Nanog induces hyperplasia without initiating tumors

by Gerrit Fischedick, Guangming Wu, Kenjiro Adachi, Marcos J. Araúzo-Bravo, Boris Greber, Martina Radstaak, Gabriele Köhler, Natalia Tapia, Roberto Iacone, Konstantinos Anastassiadis, Hans R. Schöler, Holm Zaehres
Published 2014-09-01

The in vivo timeline of differentiation of engrafted human neural progenitor cells

by Stefanie Vogel, Cordula Schäfer, Simon Hess, Kat Folz-Donahue, Melanie Nelles, Anuka Minassian, Martin K. Schwarz, Christian Kukat, Marc Ehrlich, Holm Zaehres, Peter Kloppenburg, Mathias Hoehn, Markus Aswendt
Published 2019-05-01

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

by Hyunah Lee, Hye Yeong Lee, Byeong Eun Lee, Daniela Gerovska, Soo Yong Park, Holm Zaehres, Marcos J Araúzo-Bravo, Jae-Ick Kim, Yoon Ha, Hans R Schöler, Jeong Beom Kim
Published 2020-06-01

Comparative transcriptome analysis in induced neural stem cells reveals defined neural cell identities in vitro and after transplantation into the adult rodent brain

by Anna-Lena Hallmann, Marcos J. Araúzo-Bravo, Christina Zerfass, Volker Senner, Marc Ehrlich, Olympia E. Psathaki, Dong Wook Han, Natalia Tapia, Holm Zaehres, Hans R. Schöler, Tanja Kuhlmann, Gunnar Hargus
Published 2016-05-01

Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model.

by Myung Rae Park, Man Sze Wong, Marcos J Araúzo-Bravo, Hyunah Lee, Donggyu Nam, Soo Yong Park, Hong Dae Seo, Sang Min Lee, Hans Florian Zeilhofer, Holm Zaehres, Hans R Schöler, Jeong Beom Kim
Published 2019-01-01

GAA Deficiency in Pompe Disease Is Alleviated by Exon Inclusion in iPSC-Derived Skeletal Muscle Cells

by Erik van der Wal, Atze J. Bergsma, Tom J.M. van Gestel, Stijn L.M. in ‘t Groen, Holm Zaehres, Marcos J. Araúzo-Bravo, Hans R. Schöler, Ans T. van der Ploeg, W.W.M. Pim Pijnappel
Published 2017-06-01

Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells.

by Guangming Wu, Na Liu, Ina Rittelmeyer, Amar Deep Sharma, Malte Sgodda, Holm Zaehres, Martina Bleidissel, Boris Greber, Luca Gentile, Dong Wook Han, Cornelia Rudolph, Doris Steinemann, Axel Schambach, Michael Ott, Hans R Schöler, Tobias Cantz
Published 2011-07-01

Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis

by Gemma Gomez-Giro, Jonathan Arias-Fuenzalida, Javier Jarazo, Dagmar Zeuschner, Muhammad Ali, Nina Possemis, Silvia Bolognin, Rashi Halder, Christian Jäger, Willemijn F. E. Kuper, Peter M. van Hasselt, Holm Zaehres, Antonio del Sol, Herman van der Putten, Hans R. Schöler, Jens C. Schwamborn
Published 2019-12-01

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

by Marc Ehrlich, Anna-Lena Hallmann, Peter Reinhardt, Marcos J. Araúzo-Bravo, Sabrina Korr, Albrecht Röpke, Olympia E. Psathaki, Petra Ehling, Sven G. Meuth, Adrian L. Oblak, Jill R. Murrell, Bernardino Ghetti, Holm Zaehres, Hans R. Schöler, Jared Sterneckert, Tanja Kuhlmann, Gunnar Hargus
Published 2015-07-01

Origin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain

by Gunnar Hargus, Marc Ehrlich, Marcos J. Araúzo-Bravo, Kathrin Hemmer, Anna-Lena Hallmann, Peter Reinhardt, Kee-Pyo Kim, Kenjiro Adachi, Simeon Santourlidis, Foued Ghanjati, Mareike Fauser, Christiana Ossig, Alexander Storch, Jeong Beom Kim, Jens C. Schwamborn, Jared Sterneckert, Hans R. Schöler, Tanja Kuhlmann, Holm Zaehres
Published 2014-09-01