Decoding a signature-based model of transcription cofactor recruitment dictated by cardinal cis-regulatory elements in proximal promoter regions.

by Christopher Benner, Sergiy Konovalov, Carlos Mackintosh, Kasey R Hutt, Rieka Stunnenberg, Ivan Garcia-Bassets
Published 2013-11-01

Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells

by Qi Ma, Feng Yang, Carlos Mackintosh, Ranveer Singh Jayani, Soohwan Oh, Chunyu Jin, Sreejith Janardhanan Nair, Daria Merkurjev, Wubin Ma, Stephanie Allen, Dong Wang, Angels Almenar-Queralt, Ivan Garcia-Bassets
Published 2020-04-01

Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants

by Mel·lina Pinsach-Abuin, Bernat del Olmo, Adrian Pérez-Agustin, Jesus Mates, Catarina Allegue, Anna Iglesias, Qi Ma, Daria Merkurjev, Sergiy Konovalov, Jing Zhang, Farah Sheikh, Amalio Telenti, Josep Brugada, Ramon Brugada, Melissa Gymrek, Julia di Iulio, Ivan Garcia-Bassets, Sara Pagans
Published 2021-04-01

Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

by Laure Escoubet-Lozach, Christopher Benner, Minna U Kaikkonen, Jean Lozach, Sven Heinz, Nathan J Spann, Andrea Crotti, Josh Stender, Serena Ghisletti, Donna Reichart, Christine S Cheng, Rosa Luna, Colleen Ludka, Roman Sasik, Ivan Garcia-Bassets, Alexander Hoffmann, Shankar Subramaniam, Gary Hardiman, Michael G Rosenfeld, Christopher K Glass
Published 2011-12-01