Algorithms Article Bourque distances Computational Biology Disease Progression Humans Hyperphagia LEP LEPR Labeled phylogenetic trees Leptin Leukemia, Myeloid, Acute Methylation Models, Statistical Mutation Mutation trees Prader-Willi syndrome Robinson−Foulds distance Signal Transduction The nearest neighbor interchange distance acute myeloid leukemia algorithm analytical error base pairing biology calibration cancer patient classification clonal evolution cohort analysis