Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis.

by Laura-Isobel McCall, Jair L Siqueira-Neto, James H McKerrow
Published 2016-05-01

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome.

by Laura-Isobel McCall, Anupriya Tripathi, Fernando Vargas, Rob Knight, Pieter C Dorrestein, Jair L Siqueira-Neto
Published 2018-03-01

Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi.

by Isabel S Shiratsubaki, Xin Fang, Rodolpho O O Souza, Bernhard O Palsson, Ariel M Silber, Jair L Siqueira-Neto
Published 2020-10-01

High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for <i>Trypanosoma cruzi</i>

by Jean A. Bernatchez, Emily Chen, Mitchell V. Hull, Case W. McNamara, James H. McKerrow, Jair L. Siqueira-Neto
Published 2020-03-01

Mechanism of Action of Methotrexate Against Zika Virus

by Sungjun Beck, Zhe Zhu, Michelli F. Oliveira, Davey M. Smith, Jeremy N. Rich, Jean A. Bernatchez, Jair L. Siqueira-Neto
Published 2019-04-01

Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity

by Lena Keller, Jair L. Siqueira-Neto, Julia M. Souza, Korina Eribez, Gregory M. LaMonte, Jennifer E. Smith, William H. Gerwick
Published 2020-03-01

Cysteine proteases in protozoan parasites.

by Jair L Siqueira-Neto, Anjan Debnath, Laura-Isobel McCall, Jean A Bernatchez, Momar Ndao, Sharon L Reed, Philip J Rosenthal
Published 2018-08-01

An image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruzi.

by Seunghyun Moon, Jair L Siqueira-Neto, Carolina Borsoi Moraes, Gyongseon Yang, Myungjoo Kang, Lucio H Freitas-Junior, Michael A E Hansen
Published 2014-01-01

Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways.

by Jacob M Wozniak, Tatiana Araújo Silva, Diane Thomas, Jair L Siqueira-Neto, James H McKerrow, David J Gonzalez, Claudia M Calvet
Published 2020-05-01

Dysregulation of Glycerophosphocholines in the Cutaneous Lesion Caused by <i>Leishmania major</i> in Experimental Murine Models

by Adwaita R. Parab, Diane Thomas, Sharon Lostracco-Johnson, Jair L. Siqueira-Neto, James H. McKerrow, Pieter C. Dorrestein, Laura-Isobel McCall
Published 2021-05-01

An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.

by Jair L Siqueira-Neto, Seunghyun Moon, Jiyeon Jang, Gyongseon Yang, Changbok Lee, Hong Kee Moon, Eric Chatelain, Auguste Genovesio, Jonathan Cechetto, Lucio H Freitas-Junior
Published 2012-01-01

Automated nuclear analysis of Leishmania major telomeric clusters reveals changes in their organization during the parasite's life cycle.

by Fernando de M Dossin, Alexandre Dufour, Elodie Dusch, Jair L Siqueira-Neto, Carolina B Moraes, Gyong Seon Yang, Maria Isabel Cano, Auguste Genovesio, Lucio H Freitas-Junior
Published 2008-01-01

In vitro anti-Trypanosoma cruzi activity enhancement of curcumin by its monoketone tetramethoxy analog diveratralacetone

by Julia M. Souza, Tatiana M. Vieira, Ana Carolina B.B. Candido, Daiane Y. Tezuka, G. Subba Rao, Sérgio de Albuquerque, Antônio E.M. Crotti, Jair L. Siqueira-Neto, Lizandra G. Magalhães
Published 2021-01-01

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

by Jean A. Bernatchez, Michael Coste, Sungjun Beck, Grace A. Wells, Lucas A. Luna, Alex E. Clark, Zhe Zhu, David Hecht, Jeremy N. Rich, Christal D. Sohl, Byron W. Purse, Jair L. Siqueira-Neto
Published 2019-04-01

Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.

by Jair L Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh, Jeong-Hun Sohn, Gyongseon Yang, Jiyoun Nam, Jiyeon Jang, Jonathan Cechetto, Chang Bok Lee, Seunghyun Moon, Auguste Genovesio, Eric Chatelain, Thierry Christophe, Lucio H Freitas-Junior
Published 2010-01-01

Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase.

by Laura-Isobel McCall, Amale El Aroussi, Jun Yong Choi, Debora F Vieira, Geraldine De Muylder, Jonathan B Johnston, Steven Chen, Danielle Kellar, Jair L Siqueira-Neto, William R Roush, Larissa M Podust, James H McKerrow
Published 2015-03-01