Identification of mutations in the PYRIN-containing NLR genes (NLRP) in Head and Neck Squamous Cell Carcinoma.

by Yu Lei, Vivian W Y Lui, Jennifer R Grandis, Ann Marie Egloff
Published 2014-01-01

Targeting STAT3 in Cancer with Nucleotide Therapeutics

by Yue-Ting K. Lau, Malini Ramaiyer, Daniel E. Johnson, Jennifer R. Grandis
Published 2019-10-01

STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors.

by Thiruganesh Ramasamy, Xucai Chen, Bin Qin, Daniel E Johnson, Jennifer R Grandis, Flordeliza S Villanueva
Published 2020-01-01

Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance.

by Rachel A O'Keefe, Neil E Bhola, David S Lee, Daniel E Johnson, Jennifer R Grandis
Published 2020-01-01

STAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinoma.

by Jonah D Klein, Daisuke Sano, Malabika Sen, Jeffrey N Myers, Jennifer R Grandis, Seungwon Kim
Published 2014-01-01

Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor

by David S. Lee, Rachel A. O’Keefe, Patrick K. Ha, Jennifer R. Grandis, Daniel E. Johnson
Published 2018-05-01

Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction

by Zhibin Cui, Hadas Dabas, Brandon C. Leonard, Jamie V. Shiah, Jennifer R. Grandis, Daniel E. Johnson
Published 2021-08-01

Targeting Antiapoptotic Bcl-2 Family Members with Cell-Permeable BH3 Peptides Induces Apoptosis Signaling, Death in Head, Neck Squamous Cell Carcinoma Cells

by Rongxiu Li, Amanda L. Boehm, Michelle B. Miranda, Sanjeev Shangary, Jennifer R. Grandis, Daniel E Johnson
Published 2007-10-01

Challenges in EGFRvIII detection in head and neck squamous cell carcinoma.

by Sarah E Wheeler, Ann Marie Egloff, Lin Wang, C David James, Peter S Hammerman, Jennifer R Grandis
Published 2015-01-01

STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors

by Thiruganesh Ramasamy, Xucai Chen, Bin Qin, Daniel E. Johnson, Jennifer R. Grandis, Flordeliza S. Villanueva, Irina V. Lebedeva
Published 2020-01-01

Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer.

by Noah D Peyser, Yu Du, Hua Li, Vivian Lui, Xiao Xiao, Timothy A Chan, Jennifer R Grandis
Published 2015-01-01

Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer.

by Noah D Peyser, Kelsey Pendleton, William E Gooding, Vivian W Y Lui, Daniel E Johnson, Jennifer R Grandis
Published 2016-01-01

Targeting TORC1/2 Enhances Sensitivity to EGFR Inhibitors in Head and Neck Cancer Preclinical Models

by Andre Cassell, Maria L Freilino, Jessica Lee, Sharon Barr, Lin Wang, Mary C Panahandeh, Sufi M Thomas, Jennifer R Grandis
Published 2012-11-01

Quantifying metabolic heterogeneity in head and neck tumors in real time: 2-DG uptake is highest in hypoxic tumor regions.

by Erica C Nakajima, Charles Laymon, Matthew Oborski, Weizhou Hou, Lin Wang, Jennifer R Grandis, Robert L Ferris, James M Mountz, Bennett Van Houten
Published 2014-01-01

Clinical trials optimizing investigator and self‐collection of buccal cells for RNA yield

by Jessica L. Geiger, Elizabeth D. Cedars, Yan Zang, Daniel P. Normolle, Hua Li, Jennifer R. Grandis, Sara Centuori, Daniel E. Johnson, Julie E. Bauman
Published 2021-02-01

PD-1+CXCR5−CD4+ Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma

by Shu-Mei Yan, Jiang-Ping Li, Chang-You Wu, Ming-Yuan Chen, Shang-Xin Liu, Yin-Feng Kang, Cong Sun, Jennifer R Grandis, Mu-Sheng Zeng, Qian Zhong
Published 2021-07-01

JAK Kinase Inhibition Abrogates STAT3 Activation and Head and Neck Squamous Cell Carcinoma Tumor Growth

by Malabika Sen, Netanya I. Pollock, John Black, Kara A. DeGrave, Sarah Wheeler, Maria L. Freilino, Sonali Joyce, Vivian W.Y. Lui, Yan Zeng, Simion I. Chiosea, Jennifer R. Grandis
Published 2015-03-01

Phase I Study of Ficlatuzumab and Cetuximab in Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Cancer

by Julie E. Bauman, James Ohr, William E. Gooding, Robert L. Ferris, Umamaheswar Duvvuri, Seungwon Kim, Jonas T. Johnson, Adam C. Soloff, Gerald Wallweber, John Winslow, Autumn Gaither-Davis, Jennifer R. Grandis, Laura P. Stabile
Published 2020-06-01

Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma

by Liyong Zhang, Zhihong Li, Yehai Liu, Shuping Xu, Manuj Tandon, Brittany Appelboom, Courtney R. LaValle, Simion I. Chiosea, Lin Wang, Malabika Sen, Vivian W. Y. Lui, Jennifer R. Grandis, Q. Jane Wang
Published 2018-11-01

IGF2 Mediates Resistance to Isoform-Selective-Inhibitors of the PI3K in HPV Positive Head and Neck Cancer

by Mai Badarni, Manu Prasad, Artemiy Golden, Baisali Bhattacharya, Liron Levin, Ksenia M. Yegodayev, Orr Dimitstein, Ben-Zion Joshua, Limor Cohen, Ekaterina Khrameeva, Dexin Kong, Angel Porgador, Alex Braiman, Jennifer R. Grandis, Barak Rotblat, Moshe Elkabets
Published 2021-05-01