The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development

by Aimee Tan, John M Atack, Michael P Jennings, Kate L Seib
Published 2016-12-01

Systematic Analysis of REBASE Identifies Numerous Type I Restriction-Modification Systems with Duplicated, Distinct hsdS Specificity Genes That Can Switch System Specificity by Rec...

by John M. Atack, Chengying Guo, Thomas Litfin, Long Yang, Patrick J. Blackall, Yaoqi Zhou, Michael P. Jennings
Published 2020-07-01

Moraxella catarrhalis phase-variable loci show differences in expression during conditions relevant to disease.

by Aimee Tan, Luke V Blakeway, Taha, Yuedong Yang, Yaoqi Zhou, John M Atack, Ian R Peak, Kate L Seib
Published 2020-01-01

The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media

by Luke V. Blakeway, Aimee Tan, Joseph A. Jurcisek, Lauren O. Bakaletz, John M. Atack, Ian R. Peak, Kate L. Seib
Published 2019-12-01

Selection for phase variation of LOS biosynthetic genes frequently occurs in progression of non-typeable Haemophilus influenzae infection from the nasopharynx to the middle ear of...

by Kate L Fox, John M Atack, Yogitha N Srikhanta, Anja Eckert, Laura A Novotny, Lauren O Bakaletz, Michael P Jennings
Published 2014-01-01

The ModA2 Phasevarion of nontypeable Haemophilus influenzae Regulates Resistance to Oxidative Stress and Killing by Human Neutrophils

by Kenneth L. Brockman, M. Taylor Branstool, John M. Atack, Frank Robledo-Avila, Santiago Partida-Sanchez, Michael P. Jennings, Lauren O. Bakaletz
Published 2017-06-01

Streptococcus suis Encodes Multiple Allelic Variants of a Phase-Variable Type III DNA Methyltransferase, ModS, That Control Distinct Phasevarions

by Greg Tram, Freda E.-C. Jen, Zachary N. Phillips, Jamie Timms, Asma-Ul Husna, Michael P. Jennings, Patrick J. Blackall, John M. Atack
Published 2021-06-01

Epigenetic Regulation Alters Biofilm Architecture and Composition in Multiple Clinical Isolates of Nontypeable Haemophilus influenzae

by Kenneth L. Brockman, Patrick N. Azzari, M. Taylor Branstool, John M. Atack, Benjamin L. Schulz, Freda E.-C. Jen, Michael P. Jennings, Lauren O. Bakaletz
Published 2018-09-01

Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N-Acetylneuraminic Acid as a Host Adaptation

by Preston S. K. Ng, Christopher J. Day, John M. Atack, Lauren E. Hartley-Tassell, Linda E. Winter, Tal Marshanski, Vered Padler-Karavani, Ajit Varki, Stephen J. Barenkamp, Michael A. Apicella, Michael P. Jennings
Published 2019-05-01