A retinoic acid receptor β agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord

by Marta Agudo, Ping Yip, Meirion Davies, Elizabeth Bradbury, Patrick Doherty, Stephen McMahon, Malcolm Maden, Jonathan P.T. Corcoran
Published 2010-01-01

Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth

by Maria B. Goncalves, Yue Wu, Diogo Trigo, Earl Clarke, Tony Malmqvist, John Grist, Carl Hobbs, Thomas P. Carlstedt, Jonathan P.T. Corcoran
Published 2018-03-01

RARβ Agonist Drug (C286) Demonstrates Efficacy in a Pre-clinical Neuropathic Pain Model Restoring Multiple Pathways via DNA Repair Mechanisms

by Maria B. Goncalves, Julien Moehlin, Earl Clarke, John Grist, Carl Hobbs, Antony M. Carr, Julian Jack, Marco Antonio Mendoza-Parra, Jonathan P.T. Corcoran
Published 2019-10-01