A novel simple method for determining CYP2D6 gene copy number and identifying allele(s) with duplication/multiplication.

by Taimour Langaee, Issam Hamadeh, Arlene B Chapman, John G Gums, Julie A Johnson
Published 2015-01-01

Chromosome 7 and 19 trisomy in cultured human neural progenitor cells.

by Dhruv Sareen, Erin McMillan, Allison D Ebert, Brandon C Shelley, Julie A Johnson, Lorraine F Meisner, Clive N Svendsen
Published 2009-10-01

Clinical Utility of Pharmacogene Panel‐Based Testing in Patients Undergoing Percutaneous Coronary Intervention

by Nihal El Rouby, Adel Alrwisan, Taimour Langaee, Gloria Lipori, Dominick J Angiolillo, Francesco Franchi, Alberto Riva, Amanda Elsey, Julie A. Johnson, Larisa H. Cavallari, Almut G. Winterstein
Published 2020-05-01

Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients

by Mai Mehanna, Caitrin W. McDonough, Steven M. Smith, Yan Gong, John G. Gums, Arlene B. Chapman, Julie A. Johnson, Lauren McIntyre, Rhonda M. Cooper-DeHoff
Published 2021-09-01

Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals.

by MyPhuong T Le, Maximilian T Lobmeyer, Marcus Campbell, Jing Cheng, Zhiying Wang, Stephen T Turner, Arlene B Chapman, Eric Boerwinkle, John G Gums, Yan Gong, Richard J Johnson, Julie A Johnson
Published 2013-01-01

Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.

by Patrick N Cunningham, Zhiying Wang, Megan L Grove, Rhonda M Cooper-DeHoff, Amber L Beitelshees, Yan Gong, John G Gums, Julie A Johnson, Stephen T Turner, Eric Boerwinkle, Arlene B Chapman
Published 2019-01-01

Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention

by Larisa H. Cavallari, Francesco Franchi, Fabiana Rollini, Latonya Been, Andrea Rivas, Malhar Agarwal, D. Max Smith, Kimberly Newsom, Yan Gong, Amanda R. Elsey, Petr Starostik, Julie A. Johnson, Dominick J. Angiolillo
Published 2018-04-01

Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta‐Blockers in European Americans

by Sonal Singh, Nihal El Rouby, Caitrin W. McDonough, Yan Gong, Kent R. Bailey, Eric Boerwinkle, Arlene B. Chapman, John G. Gums, Stephen T. Turner, Rhonda M. Cooper‐DeHoff, Julie A. Johnson
Published 2019-09-01

Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.

by Audrey C Papp, Julia K Pinsonneault, Danxin Wang, Leslie C Newman, Yan Gong, Julie A Johnson, Carl J Pepine, Meena Kumari, Aroon D Hingorani, Philippa J Talmud, Sonia Shah, Steve E Humphries, Wolfgang Sadee
Published 2012-01-01

Pharmacometabolomics reveals racial differences in response to atenolol treatment.

by William R Wikoff, Reginald F Frye, Hongjie Zhu, Yan Gong, Stephen Boyle, Erik Churchill, Rhonda M Cooper-Dehoff, Amber L Beitelshees, Arlene B Chapman, Oliver Fiehn, Julie A Johnson, Rima Kaddurah-Daouk, Pharmacometabolomics Research Network
Published 2013-01-01

Aromatase gene polymorphisms are associated with survival among patients with cardiovascular disease in a sex-specific manner.

by Amber L Beitelshees, Julie A Johnson, Megan L Hames, Yan Gong, Rhonda M Cooper-Dehoff, Jun Wu, Sharon Cresci, Cynthia X Ma, Carl J Pepine, Michael A Province, John A Spertus, Howard L McLeod
Published 2010-12-01

Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network

by Nina R. Sperber, Olivia M. Dong, Megan C. Roberts, Paul Dexter, Amanda R. Elsey, Geoffrey S. Ginsburg, Carol R. Horowitz, Julie A. Johnson, Kenneth D. Levy, Henry Ong, Josh F. Peterson, Toni I. Pollin, Tejinder Rakhra-Burris, Michelle A. Ramos, Todd Skaar, Lori A. Orlando
Published 2021-07-01

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies

by Ana Caroline C. Sá, Amy Webb, Yan Gong, Caitrin W. McDonough, Mohamed H. Shahin, Somnath Datta, Taimour Y. Langaee, Stephen T. Turner, Amber L. Beitelshees, Arlene B. Chapman, Eric Boerwinkle, John G. Gums, Steven E. Scherer, Rhonda M. Cooper-DeHoff, Wolfgang Sadee, Julie A. Johnson
Published 2018-06-01

Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic

by Meghan J. Arwood, Eric A. Dietrich, Benjamin Q. Duong, D. Max Smith, Kelsey Cook, Amanda Elchynski, Eric I. Rosenberg, Katherine N. Huber, Ying L. Nagoshi, Ashleigh Wright, Jeffrey T. Budd, Neal P. Holland, Edlira Maska, Danielle Panna, Amanda R. Elsey, Larisa H. Cavallari, Kristin Wiisanen, Julie A. Johnson, John G. Gums
Published 2020-07-01

Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.

by Caitrin W McDonough, Nancy K Gillis, Abdullah Alsultan, Shin-Wen Chang, Marina Kawaguchi-Suzuki, Jason E Lang, Mohamed Hossam A Shahin, Thomas W Buford, Nihal M El Rouby, Ana C C Sá, Taimour Y Langaee, John G Gums, Arlene B Chapman, Rhonda M Cooper-DeHoff, Stephen T Turner, Yan Gong, Julie A Johnson
Published 2013-01-01

Genome-wide study of resistant hypertension identified from electronic health records.

by Logan Dumitrescu, Marylyn D Ritchie, Joshua C Denny, Nihal M El Rouby, Caitrin W McDonough, Yuki Bradford, Andrea H Ramirez, Suzette J Bielinski, Melissa A Basford, High Seng Chai, Peggy Peissig, David Carrell, Jyotishman Pathak, Luke V Rasmussen, Xiaoming Wang, Jennifer A Pacheco, Abel N Kho, M Geoffrey Hayes, Martha Matsumoto, Maureen E Smith, Rongling Li, Rhonda M Cooper-DeHoff, Iftikhar J Kullo, Christopher G Chute, Rex L Chisholm, Gail P Jarvik, Eric B Larson, David Carey, Catherine A McCarty, Marc S Williams, Dan M Roden, Erwin Bottinger, Julie A Johnson, Mariza de Andrade, Dana C Crawford
Published 2017-01-01